HCSGD entry for SLC39A1
1. General information
| Official gene symbol | SLC39A1 |
|---|---|
| Entrez ID | 27173 |
| Gene full name | solute carrier family 39 (zinc transporter), member 1 |
| Other gene symbols | ZIP1 ZIRTL |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005102 | Receptor binding | IEA | molecular_function |
| GO:0005385 | Zinc ion transmembrane transporter activity | IEA | molecular_function |
| GO:0005789 | Endoplasmic reticulum membrane | IEA | cellular_component |
| GO:0005886 | Plasma membrane | IDA TAS | cellular_component |
| GO:0006812 | Cation transport | TAS | biological_process |
| GO:0016020 | Membrane | IEA TAS | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0022890 | Inorganic cation transmembrane transporter activity | TAS | molecular_function |
| GO:0046873 | Metal ion transmembrane transporter activity | IEA | molecular_function |
| GO:0055085 | Transmembrane transport | TAS | biological_process |
| GO:0071577 | Zinc ion transmembrane transport | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9546423350 | 0.0318692641 | 0.9999902473 | 0.3355728800 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1820317780 |
| GSE13712_SHEAR | Up | 0.0220000791 |
| GSE13712_STATIC | Down | -0.0788027454 |
| GSE19018 | Down | -0.0238449367 |
| GSE19899_A1 | Down | -0.6925076101 |
| GSE19899_A2 | Down | -0.5113226638 |
| PubMed_21979375_A1 | Down | -1.0069661436 |
| PubMed_21979375_A2 | Down | -0.5831110725 |
| GSE35957 | Down | -0.1028054105 |
| GSE36640 | Down | -0.0262547236 |
| GSE54402 | Down | -0.6176568358 |
| GSE9593 | Down | -0.0503307336 |
| GSE43922 | Down | -0.5452642758 |
| GSE24585 | Up | 0.0497978490 |
| GSE37065 | Up | 0.0102271833 |
| GSE28863_A1 | Up | 0.1626871171 |
| GSE28863_A2 | Up | 0.3449125267 |
| GSE28863_A3 | Down | -0.5050314519 |
| GSE28863_A4 | Down | -0.3064134957 |
| GSE48662 | Down | -0.0188099178 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-215-5p | MIMAT0000272 | MIRT024724 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026105 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-96-5p | MIMAT0000095 | MIRT027938 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-877-5p | MIMAT0004949 | MIRT037329 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-30c-5p | MIMAT0000244 | MIRT047939 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
