HCSGD entry for INVS


1. General information

Official gene symbolINVS
Entrez ID27130
Gene full nameinversin
Other gene symbolsINV NPH2 NPHP2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001822Kidney developmentIEAbiological_process
GO:0005515Protein bindingIPImolecular_function
GO:0005516Calmodulin bindingIEAmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0005737CytoplasmIEAcellular_component
GO:0005819SpindleIEAcellular_component
GO:0005874MicrotubuleIEAcellular_component
GO:0005929CiliumIEAcellular_component
GO:0009791Post-embryonic developmentIEAbiological_process
GO:0016020MembraneIEAcellular_component
GO:0016055Wnt signaling pathwayIEAbiological_process
GO:0031016Pancreas developmentIEAbiological_process
GO:0060971Embryonic heart tube left/right pattern formationIEAbiological_process
GO:0090090Negative regulation of canonical Wnt signaling pathwayIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.91283440600.51265953420.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0743786292
GSE13712_SHEARDown-0.0092568072
GSE13712_STATICDown-0.0314573232
GSE19018Up0.0578158766
GSE19899_A1Down-0.1451447241
GSE19899_A2Down-0.0200841243
PubMed_21979375_A1Down-0.3256771552
PubMed_21979375_A2Down-0.0820904886
GSE35957Down-0.0187158067
GSE36640Down-0.1118420499
GSE54402Down-0.0949165168
GSE9593Down-0.0244611801
GSE43922Down-0.3634597503
GSE24585Up0.1457315209
GSE37065Up0.0358916613
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Up0.2121499606

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.