HCSGD entry for GK
1. General information
| Official gene symbol | GK |
|---|---|
| Entrez ID | 2710 |
| Gene full name | glycerol kinase |
| Other gene symbols | GK1 GKD |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004370 | Glycerol kinase activity | IMP NAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005741 | Mitochondrial outer membrane | IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005975 | Carbohydrate metabolic process | IEA | biological_process |
| GO:0006071 | Glycerol metabolic process | IMP | biological_process |
| GO:0006641 | Triglyceride metabolic process | IMP | biological_process |
| GO:0016301 | Kinase activity | IEA | molecular_function |
| GO:0016773 | Phosphotransferase activity, alcohol group as acceptor | IEA | molecular_function |
| GO:0019432 | Triglyceride biosynthetic process | TAS | biological_process |
| GO:0019563 | Glycerol catabolic process | IEA | biological_process |
| GO:0044255 | Cellular lipid metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046167 | Glycerol-3-phosphate biosynthetic process | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0016452072 | 0.9201514912 | 0.1092238095 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 1.1945860524 |
| GSE13712_SHEAR | Down | -0.2277219739 |
| GSE13712_STATIC | Up | 0.0355913499 |
| GSE19018 | Down | -1.2432038568 |
| GSE19899_A1 | Up | 1.8107088911 |
| GSE19899_A2 | Up | 2.5030425543 |
| PubMed_21979375_A1 | Up | 2.5751749430 |
| PubMed_21979375_A2 | Up | 2.2907269549 |
| GSE35957 | Down | -0.0648764015 |
| GSE36640 | Up | 0.5536014174 |
| GSE54402 | Up | 1.2021487273 |
| GSE9593 | Down | -0.0289251645 |
| GSE43922 | - | - |
| GSE24585 | - | - |
| GSE37065 | - | - |
| GSE28863_A1 | Down | -0.1461395772 |
| GSE28863_A2 | Up | 0.0992366399 |
| GSE28863_A3 | Up | 0.2710298094 |
| GSE28863_A4 | Up | 0.1510519451 |
| GSE48662 | Up | 0.2195972500 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-132-3p | MIMAT0000426 | MIRT021809 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-10b-5p | MIMAT0000254 | MIRT047490 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord

