HCSGD entry for AMPD2
1. General information
| Official gene symbol | AMPD2 |
|---|---|
| Entrez ID | 271 |
| Gene full name | adenosine monophosphate deaminase 2 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003876 | AMP deaminase activity | IEA NAS | molecular_function |
| GO:0005575 | Cellular_component | ND | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006144 | Purine nucleobase metabolic process | TAS | biological_process |
| GO:0006188 | IMP biosynthetic process | IEA | biological_process |
| GO:0032264 | IMP salvage | IEA | biological_process |
| GO:0043101 | Purine-containing compound salvage | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0055086 | Nucleobase-containing small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0494461343 | 0.4476335929 | 0.4882649813 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3993295228 |
| GSE13712_SHEAR | Down | -0.4607120710 |
| GSE13712_STATIC | Up | 0.0458068890 |
| GSE19018 | Up | 0.3452302235 |
| GSE19899_A1 | Down | -0.0461027723 |
| GSE19899_A2 | Up | 0.6134668847 |
| PubMed_21979375_A1 | Up | 0.8521145578 |
| PubMed_21979375_A2 | Up | 1.6287810177 |
| GSE35957 | Down | -0.3227047201 |
| GSE36640 | Up | 0.0955192978 |
| GSE54402 | Up | 0.6316864320 |
| GSE9593 | Down | -0.2283401959 |
| GSE43922 | Up | 0.0047820410 |
| GSE24585 | Down | -0.7532972847 |
| GSE37065 | Down | -0.1592281487 |
| GSE28863_A1 | Up | 0.2932013079 |
| GSE28863_A2 | Up | 0.5687210857 |
| GSE28863_A3 | Down | -0.3686878307 |
| GSE28863_A4 | Down | -0.2841322590 |
| GSE48662 | Up | 0.5002788966 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-939-5p | MIMAT0004982 | MIRT036636 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT041932 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-10a-5p | MIMAT0000253 | MIRT047663 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-24-3p | MIMAT0000080 | MIRT050367 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7e-5p | MIMAT0000066 | MIRT051656 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7a-5p | MIMAT0000062 | MIRT052568 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
