HCSGD entry for GJB3


1. General information

Official gene symbolGJB3
Entrez ID2707
Gene full namegap junction protein, beta 3, 31kDa
Other gene symbolsCX31 DFNA2 DFNA2B EKV
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001701In utero embryonic developmentIEAbiological_process
GO:0001890Placenta developmentIEAbiological_process
GO:0005243Gap junction channel activityNASmolecular_function
GO:0005737CytoplasmIEAcellular_component
GO:0005921Gap junctionNAScellular_component
GO:0005922Connexon complexIEAcellular_component
GO:0006810TransportNASbiological_process
GO:0007154Cell communicationIEAbiological_process
GO:0007605Sensory perception of soundIEAbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0043588Skin developmentIEAbiological_process
GO:0055085Transmembrane transportNASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.83678811220.65197533530.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0599129706
GSE13712_SHEARUp0.0765371564
GSE13712_STATICUp0.0070771447
GSE19018Down-0.0161088571
GSE19899_A1Up0.1227641683
GSE19899_A2Up0.0994430403
PubMed_21979375_A1Up0.0576890172
PubMed_21979375_A2Up0.0378985973
GSE35957Up0.0381788525
GSE36640Up0.0343389795
GSE54402Down-0.0284888461
GSE9593Down-0.0305142034
GSE43922Up0.0125839734
GSE24585Up0.0086482958
GSE37065Down-0.0275337083
GSE28863_A1Down-0.1656815197
GSE28863_A2Down-0.2947239327
GSE28863_A3Up0.2391438630
GSE28863_A4Up0.0320247758
GSE48662Down-0.0297994944

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-1MIMAT0000416MIRT023520MicroarrayFunctional MTI (Weak)18668037
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.