HCSGD entry for PPA2
1. General information
| Official gene symbol | PPA2 |
|---|---|
| Entrez ID | 27068 |
| Gene full name | pyrophosphatase (inorganic) 2 |
| Other gene symbols | SID6-306 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000287 | Magnesium ion binding | IEA | molecular_function |
| GO:0004427 | Inorganic diphosphatase activity | IEA TAS | molecular_function |
| GO:0004722 | Protein serine/threonine phosphatase activity | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005739 | Mitochondrion | IEA | cellular_component |
| GO:0005759 | Mitochondrial matrix | TAS | cellular_component |
| GO:0006418 | TRNA aminoacylation for protein translation | TAS | biological_process |
| GO:0006796 | Phosphate-containing compound metabolic process | IEA | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0071344 | Diphosphate metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2271164279 | 0.7005964401 | 0.9085002280 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1599186607 |
| GSE13712_SHEAR | Up | 0.0719010269 |
| GSE13712_STATIC | Up | 0.0611804672 |
| GSE19018 | Down | -0.0241297264 |
| GSE19899_A1 | Up | 0.2081122645 |
| GSE19899_A2 | Up | 0.6673567645 |
| PubMed_21979375_A1 | Up | 0.8999311247 |
| PubMed_21979375_A2 | Up | 0.3866945036 |
| GSE35957 | Down | -0.1322250600 |
| GSE36640 | Down | -0.0807383259 |
| GSE54402 | Up | 0.3849093952 |
| GSE9593 | Down | -0.2423043289 |
| GSE43922 | Up | 0.0537491510 |
| GSE24585 | Down | -0.1430405806 |
| GSE37065 | Up | 0.0916910764 |
| GSE28863_A1 | Down | -0.1151444503 |
| GSE28863_A2 | Down | -0.1413488373 |
| GSE28863_A3 | Down | -0.4547387628 |
| GSE28863_A4 | Down | -0.3197700781 |
| GSE48662 | Up | 0.2894931150 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-193b-3p | MIMAT0002819 | MIRT016388 | Proteomics | Functional MTI (Weak) | 21512034 |
| hsa-miR-1 | MIMAT0000416 | MIRT023639 | Proteomics | Functional MTI (Weak) | 18668040 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
