HCSGD entry for DNAJC2
1. General information
| Official gene symbol | DNAJC2 |
|---|---|
| Entrez ID | 27000 |
| Gene full name | DnaJ (Hsp40) homolog, subfamily C, member 2 |
| Other gene symbols | MPHOSPH11 MPP11 ZRF1 ZUO1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003682 | Chromatin binding | IDA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005829 | Cytosol | IDA | cellular_component |
| GO:0006260 | DNA replication | IEA | biological_process |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0016568 | Chromatin modification | IEA | biological_process |
| GO:0030308 | Negative regulation of cell growth | IEA | biological_process |
| GO:0030544 | Hsp70 protein binding | IPI | molecular_function |
| GO:0031965 | Nuclear membrane | IDA | cellular_component |
| GO:0042393 | Histone binding | IDA | molecular_function |
| GO:0043130 | Ubiquitin binding | IDA | molecular_function |
| GO:0045893 | Positive regulation of transcription, DNA-templated | IDA | biological_process |
| GO:0051083 | 'de novo' cotranslational protein folding | TAS | biological_process |
| GO:2000279 | Negative regulation of DNA biosynthetic process | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2492978496 | 0.5750962805 | 0.9379314894 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2127916810 |
| GSE13712_SHEAR | Up | 0.1854834676 |
| GSE13712_STATIC | Up | 0.1273067616 |
| GSE19018 | Down | -0.6018465678 |
| GSE19899_A1 | Up | 0.2638007083 |
| GSE19899_A2 | Up | 0.3584085373 |
| PubMed_21979375_A1 | Up | 0.3541001723 |
| PubMed_21979375_A2 | Up | 0.1484406122 |
| GSE35957 | Down | -0.2690585992 |
| GSE36640 | Down | -0.1405273075 |
| GSE54402 | Up | 0.2827541865 |
| GSE9593 | Down | -0.2093102920 |
| GSE43922 | Up | 0.0789567259 |
| GSE24585 | Down | -0.5959451007 |
| GSE37065 | Down | -0.0277284764 |
| GSE28863_A1 | Up | 0.1498564362 |
| GSE28863_A2 | Up | 0.4329180070 |
| GSE28863_A3 | Up | 0.0596953285 |
| GSE28863_A4 | Down | -0.0149532699 |
| GSE48662 | Down | -0.4309062318 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-375 | MIMAT0000728 | MIRT019698 | Microarray | Functional MTI (Weak) | 20215506 |
| hsa-miR-155-5p | MIMAT0000646 | MIRT020515 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-30a-5p | MIMAT0000087 | MIRT028442 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT028835 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031386 | Proteomics | Functional MTI (Weak) | 18668040 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
