HCSGD entry for GJA3
1. General information
| Official gene symbol | GJA3 |
|---|---|
| Entrez ID | 2700 |
| Gene full name | gap junction protein, alpha 3, 46kDa |
| Other gene symbols | CX46 CZP3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005243 | Gap junction channel activity | IEA | molecular_function |
| GO:0005922 | Connexon complex | IEA | cellular_component |
| GO:0006810 | Transport | NAS | biological_process |
| GO:0007267 | Cell-cell signaling | TAS | biological_process |
| GO:0007601 | Visual perception | TAS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9107770032 | 0.2176382394 | 0.9999902473 | 0.8981586861 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0849043800 |
| GSE13712_SHEAR | Down | -0.0115388608 |
| GSE13712_STATIC | Up | 0.0262510113 |
| GSE19018 | Up | 0.0486767291 |
| GSE19899_A1 | Down | -0.0771091084 |
| GSE19899_A2 | Down | -0.2673986641 |
| PubMed_21979375_A1 | Down | -0.1517076654 |
| PubMed_21979375_A2 | Up | 0.1431023149 |
| GSE35957 | Up | 0.1106399829 |
| GSE36640 | Down | -0.3590785112 |
| GSE54402 | Down | -0.5383636441 |
| GSE9593 | Up | 0.0839860821 |
| GSE43922 | Up | 0.1410000516 |
| GSE24585 | Down | -0.2579839733 |
| GSE37065 | Down | -0.0236152332 |
| GSE28863_A1 | Down | -0.2824879720 |
| GSE28863_A2 | Down | -0.1973153702 |
| GSE28863_A3 | Up | 0.2647915865 |
| GSE28863_A4 | Up | 0.0494490182 |
| GSE48662 | Down | -0.0751664906 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-149-5p | MIMAT0000450 | MIRT045585 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
