HCSGD entry for CYFIP2
1. General information
| Official gene symbol | CYFIP2 |
|---|---|
| Entrez ID | 26999 |
| Gene full name | cytoplasmic FMR1 interacting protein 2 |
| Other gene symbols | PIR121 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IDA IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006915 | Apoptotic process | IDA | biological_process |
| GO:0016337 | Cell-cell adhesion | IDA | biological_process |
| GO:0030054 | Cell junction | IEA | cellular_component |
| GO:0038096 | Fc-gamma receptor signaling pathway involved in phagocytosis | TAS | biological_process |
| GO:0043005 | Neuron projection | IEA | cellular_component |
| GO:0045087 | Innate immune response | TAS | biological_process |
| GO:0045202 | Synapse | IDA | cellular_component |
| GO:0045862 | Positive regulation of proteolysis | IDA | biological_process |
| GO:0048471 | Perinuclear region of cytoplasm | IDA | cellular_component |
| GO:0097202 | Activation of cysteine-type endopeptidase activity | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0732569393 | 0.4551873105 | 0.5760942721 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3909273849 |
| GSE13712_SHEAR | Down | -2.1156586769 |
| GSE13712_STATIC | Down | -0.7137022400 |
| GSE19018 | Up | 0.0063015677 |
| GSE19899_A1 | Up | 0.0883432772 |
| GSE19899_A2 | Up | 0.5236643157 |
| PubMed_21979375_A1 | Up | 0.0974874528 |
| PubMed_21979375_A2 | Up | 1.3167436073 |
| GSE35957 | Down | -0.6950366722 |
| GSE36640 | Up | 0.4440307979 |
| GSE54402 | Down | -0.2826883105 |
| GSE9593 | Up | 0.1993600985 |
| GSE43922 | Up | 0.5754079883 |
| GSE24585 | Down | -0.2681100946 |
| GSE37065 | Up | 0.6421732346 |
| GSE28863_A1 | Up | 0.0810155324 |
| GSE28863_A2 | Up | 0.1269261617 |
| GSE28863_A3 | Up | 0.1719819339 |
| GSE28863_A4 | Up | 0.0523430910 |
| GSE48662 | Up | 0.0641158373 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-423-3p | MIMAT0001340 | MIRT042505 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-149-5p | MIMAT0000450 | MIRT045595 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
