HCSGD entry for AKAP8L
1. General information
| Official gene symbol | AKAP8L |
|---|---|
| Entrez ID | 26993 |
| Gene full name | A kinase (PRKA) anchor protein 8-like |
| Other gene symbols | HA95 HAP95 NAKAP NAKAP95 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA TAS | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0008150 | Biological_process | ND | biological_process |
| GO:0016363 | Nuclear matrix | IDA | cellular_component |
| GO:0017151 | DEAD/H-box RNA helicase binding | TAS | molecular_function |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1740160898 | 0.9594559819 | 0.8192233053 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1669083743 |
| GSE13712_SHEAR | Up | 0.1275951966 |
| GSE13712_STATIC | Up | 0.0363315311 |
| GSE19018 | Up | 0.0714414728 |
| GSE19899_A1 | Up | 0.0605764606 |
| GSE19899_A2 | Up | 0.4142228099 |
| PubMed_21979375_A1 | Up | 0.0006719587 |
| PubMed_21979375_A2 | Up | 0.1736696493 |
| GSE35957 | Down | -0.0572791110 |
| GSE36640 | Up | 0.3186645963 |
| GSE54402 | Up | 0.0734926201 |
| GSE9593 | Up | 0.0785081806 |
| GSE43922 | Up | 0.3570540295 |
| GSE24585 | Up | 0.2476936570 |
| GSE37065 | Up | 0.1902366651 |
| GSE28863_A1 | Down | -0.1817987741 |
| GSE28863_A2 | Down | -0.2304503570 |
| GSE28863_A3 | Up | 0.1069072563 |
| GSE28863_A4 | Down | -0.0678129999 |
| GSE48662 | Up | 0.3186746764 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-615-3p | MIMAT0003283 | MIRT040300 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-378a-5p | MIMAT0000731 | MIRT043966 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-31-5p | MIMAT0000089 | MIRT049869 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
