HCSGD entry for GHSR

1. General information

Official gene symbolGHSR
Entrez ID2693
Gene full namegrowth hormone secretagogue receptor
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001616Growth hormone secretagogue receptor activityIDAmolecular_function
GO:0004930G-protein coupled receptor activityIDAmolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0007186G-protein coupled receptor signaling pathwayIDAbiological_process
GO:0008154Actin polymerization or depolymerizationIDAbiological_process
GO:0008343Adult feeding behaviorISSbiological_process
GO:0009725Response to hormoneIDAbiological_process
GO:0009755Hormone-mediated signaling pathwayIDAbiological_process
GO:0009986Cell surfaceIDAcellular_component
GO:0016021Integral component of membraneIEAcellular_component
GO:0016520Growth hormone-releasing hormone receptor activityIDAmolecular_function
GO:0017046Peptide hormone bindingIEAmolecular_function
GO:0030252Growth hormone secretionTASbiological_process
GO:0032094Response to foodIEAbiological_process
GO:0032100Positive regulation of appetiteISSbiological_process
GO:0032691Negative regulation of interleukin-1 beta productionIDAbiological_process
GO:0032869Cellular response to insulin stimulusIEAbiological_process
GO:0040018Positive regulation of multicellular organism growthIMPbiological_process
GO:0042536Negative regulation of tumor necrosis factor biosynthetic processIDAbiological_process
GO:0043005Neuron projectionIDAcellular_component
GO:0043134Regulation of hindgut contractionIEAbiological_process
GO:0043568Positive regulation of insulin-like growth factor receptor signaling pathwayIEAbiological_process
GO:0045121Membrane raftIDAcellular_component
GO:0045409Negative regulation of interleukin-6 biosynthetic processIDAbiological_process
GO:0045923Positive regulation of fatty acid metabolic processIEAbiological_process
GO:0046676Negative regulation of insulin secretionIEAbiological_process
GO:0046697DecidualizationIDAbiological_process
GO:0050728Negative regulation of inflammatory responseIDAbiological_process
GO:0051963Regulation of synapse assemblyIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.42359974920.89650904220.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1218140559
GSE13712_SHEARDown-0.0273142485
GSE13712_STATICUp0.0959739512
GSE19018Up0.0718963795
GSE19899_A1Up0.0806794278
GSE19899_A2Up0.0375839346
PubMed_21979375_A1Up0.1067775319
PubMed_21979375_A2Up0.0757094217
GSE35957Up0.1759005580
GSE36640Up0.1028830091
GSE54402Down-0.0087231682
GSE9593Up0.0404832132
GSE43922Up0.0895557364
GSE24585Up0.1715961372
GSE37065Down-0.1834907733
GSE28863_A1Up0.1565982511
GSE28863_A2Up0.3642597684
GSE28863_A3Up0.0356808470
GSE28863_A4Up0.0273890538
GSE48662Down-0.0292869698

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

TZP-101DB05657 -

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-26b-5pMIMAT0000083MIRT029715MicroarrayFunctional MTI (Weak)19088304
hsa-miR-320aMIMAT0000510MIRT044459CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.