HCSGD entry for GH1
1. General information
| Official gene symbol | GH1 |
|---|---|
| Entrez ID | 2688 |
| Gene full name | growth hormone 1 |
| Other gene symbols | GH GH-N GHN IGHD1B hGH-N |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0002092 | Positive regulation of receptor internalization | IDA | biological_process |
| GO:0005131 | Growth hormone receptor binding | IDA IPI | molecular_function |
| GO:0005148 | Prolactin receptor binding | IPI | molecular_function |
| GO:0005179 | Hormone activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005576 | Extracellular region | IEA TAS | cellular_component |
| GO:0005615 | Extracellular space | IDA | cellular_component |
| GO:0007259 | JAK-STAT cascade | IDA | biological_process |
| GO:0008083 | Growth factor activity | IPI | molecular_function |
| GO:0010535 | Positive regulation of activation of JAK2 kinase activity | IDA | biological_process |
| GO:0014068 | Positive regulation of phosphatidylinositol 3-kinase signaling | IDA | biological_process |
| GO:0015758 | Glucose transport | IDA | biological_process |
| GO:0032355 | Response to estradiol | IDA | biological_process |
| GO:0040018 | Positive regulation of multicellular organism growth | IDA IMP | biological_process |
| GO:0042517 | Positive regulation of tyrosine phosphorylation of Stat3 protein | IDA | biological_process |
| GO:0042523 | Positive regulation of tyrosine phosphorylation of Stat5 protein | IDA | biological_process |
| GO:0043406 | Positive regulation of MAP kinase activity | TAS | biological_process |
| GO:0043568 | Positive regulation of insulin-like growth factor receptor signaling pathway | IDA | biological_process |
| GO:0046427 | Positive regulation of JAK-STAT cascade | IDA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0050731 | Positive regulation of peptidyl-tyrosine phosphorylation | IDA | biological_process |
| GO:0060396 | Growth hormone receptor signaling pathway | IDA | biological_process |
| GO:0060397 | JAK-STAT cascade involved in growth hormone signaling pathway | TAS | biological_process |
| GO:0070977 | Bone maturation | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5664996961 | 0.5378326963 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0505026982 |
| GSE13712_SHEAR | Up | 0.0836250934 |
| GSE13712_STATIC | Down | -0.0038375036 |
| GSE19018 | Up | 0.0953039317 |
| GSE19899_A1 | Down | -0.0170193660 |
| GSE19899_A2 | Down | -0.0510776820 |
| PubMed_21979375_A1 | Down | -0.0194761519 |
| PubMed_21979375_A2 | Up | 0.0204535497 |
| GSE35957 | Up | 0.0241136006 |
| GSE36640 | Down | -0.0460166144 |
| GSE54402 | Up | 0.0761061915 |
| GSE9593 | Up | 0.0529509829 |
| GSE43922 | Down | -0.0023883628 |
| GSE24585 | Down | -0.0411611147 |
| GSE37065 | Down | -0.0451341007 |
| GSE28863_A1 | Up | 0.1860801414 |
| GSE28863_A2 | Up | 0.1225467562 |
| GSE28863_A3 | Up | 0.2345236051 |
| GSE28863_A4 | Down | -0.2993009300 |
| GSE48662 | Up | 0.0131870371 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
