HCSGD entry for GGT5
1. General information
| Official gene symbol | GGT5 |
|---|---|
| Entrez ID | 2687 |
| Gene full name | gamma-glutamyltransferase 5 |
| Other gene symbols | GGT-REL GGTLA1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003840 | Gamma-glutamyltransferase activity | IEA TAS | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0006508 | Proteolysis | IEA | biological_process |
| GO:0006520 | Cellular amino acid metabolic process | TAS | biological_process |
| GO:0006691 | Leukotriene metabolic process | TAS | biological_process |
| GO:0006749 | Glutathione metabolic process | IEA TAS | biological_process |
| GO:0006750 | Glutathione biosynthetic process | IEA | biological_process |
| GO:0006954 | Inflammatory response | IEA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0019369 | Arachidonic acid metabolic process | TAS | biological_process |
| GO:0019370 | Leukotriene biosynthetic process | ISS | biological_process |
| GO:0031362 | Anchored component of external side of plasma membrane | TAS | cellular_component |
| GO:0036374 | Glutathione hydrolase activity | IEA | molecular_function |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1373201474 | 0.1781286881 | 0.7466585210 | 0.8161053438 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0869394310 |
| GSE13712_SHEAR | Down | -0.1463133016 |
| GSE13712_STATIC | Up | 0.6126127232 |
| GSE19018 | Down | -0.2565265096 |
| GSE19899_A1 | Down | -0.2795891858 |
| GSE19899_A2 | Up | 0.2174763149 |
| PubMed_21979375_A1 | Up | 0.2347202810 |
| PubMed_21979375_A2 | Up | 0.1027515561 |
| GSE35957 | Up | 0.1426551566 |
| GSE36640 | Down | -0.3007381097 |
| GSE54402 | Down | -0.1531861144 |
| GSE9593 | Up | 0.0637046128 |
| GSE43922 | Up | 0.0541233667 |
| GSE24585 | Down | -0.0040237166 |
| GSE37065 | Down | -0.1797636618 |
| GSE28863_A1 | Down | -0.1212901569 |
| GSE28863_A2 | Down | -0.1790568088 |
| GSE28863_A3 | Up | 0.6530520737 |
| GSE28863_A4 | Up | 0.0921626983 |
| GSE48662 | Up | 0.4269305790 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-346 | MIMAT0000773 | MIRT004224 | Microarray | Functional MTI (Weak) | 16822819 |
| hsa-miR-335-5p | MIMAT0000765 | MIRT018343 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
