HCSGD entry for GGT1

1. General information

Official gene symbolGGT1
Entrez ID2678
Gene full namegamma-glutamyltransferase 1
Other gene symbolsCD224 D22S672 D22S732 GGT GGT 1 GTG
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002682Regulation of immune system processISSbiological_process
GO:0003840Gamma-glutamyltransferase activityIDA IEA TASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005886Plasma membraneIDA TAScellular_component
GO:0006508ProteolysisIEAbiological_process
GO:0006520Cellular amino acid metabolic processTASbiological_process
GO:0006536Glutamate metabolic processIDAbiological_process
GO:0006691Leukotriene metabolic processTASbiological_process
GO:0006749Glutathione metabolic processIEA TASbiological_process
GO:0006750Glutathione biosynthetic processISS TASbiological_process
GO:0006751Glutathione catabolic processIDAbiological_process
GO:0006805Xenobiotic metabolic processTASbiological_process
GO:0007283SpermatogenesisISSbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0019344Cysteine biosynthetic processISSbiological_process
GO:0019369Arachidonic acid metabolic processTASbiological_process
GO:0019370Leukotriene biosynthetic processIMPbiological_process
GO:0031362Anchored component of external side of plasma membraneTAScellular_component
GO:0031638Zymogen activationIDAbiological_process
GO:0036374Glutathione hydrolase activityIDAmolecular_function
GO:0044281Small molecule metabolic processTASbiological_process
GO:0050727Regulation of inflammatory responseISSbiological_process
GO:1901687Glutathione derivative biosynthetic processTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.62452892370.27468193080.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0674894655
GSE13712_SHEARDown-0.0818815725
GSE13712_STATICUp0.0021170287
GSE19018Up0.2078366851
GSE19899_A1Down-0.0358995644
GSE19899_A2Up0.1318939092
PubMed_21979375_A1Down-0.0245109428
PubMed_21979375_A2Down-0.1652268321
GSE35957Up0.2022738042
GSE36640Up0.1027791843
GSE54402Down-0.0222128945
GSE9593Down-0.0006629239
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1Down-0.4243277680
GSE28863_A2Down-0.9152276313
GSE28863_A3Up0.4316930394
GSE28863_A4Up0.0709700238
GSE48662Up0.0238311344

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

GlutathioneDB00143 NUTR00029 | EXPT01650

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.