HCSGD entry for GFI1

1. General information

Official gene symbolGFI1
Entrez ID2672
Gene full namegrowth factor independent 1 transcription repressor
Other gene symbolsGFI-1 GFI1A SCN2 ZNF163
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000083Regulation of transcription involved in G1/S transition of mitotic cell cycleTASbiological_process
GO:0000122Negative regulation of transcription from RNA polymerase II promoterIDAbiological_process
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0007638Mechanosensory behaviorIEAbiological_process
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0009996Negative regulation of cell fate specificationIEAbiological_process
GO:0010956Negative regulation of calcidiol 1-monooxygenase activityIDAbiological_process
GO:0010957Negative regulation of vitamin D biosynthetic processICbiological_process
GO:0010977Negative regulation of neuron projection developmentIDAbiological_process
GO:0016032Viral processTASbiological_process
GO:0016363Nuclear matrixIDAcellular_component
GO:0016604Nuclear bodyIDAcellular_component
GO:0017053Transcriptional repressor complexIDAcellular_component
GO:0032088Negative regulation of NF-kappaB transcription factor activityISSbiological_process
GO:0034121Regulation of toll-like receptor signaling pathwayIDAbiological_process
GO:0042472Inner ear morphogenesisIEAbiological_process
GO:0042491Auditory receptor cell differentiationIEAbiological_process
GO:0042660Positive regulation of cell fate specificationIEAbiological_process
GO:0044212Transcription regulatory region DNA bindingIDAmolecular_function
GO:0045165Cell fate commitmentIEAbiological_process
GO:0045892Negative regulation of transcription, DNA-templatedIDAbiological_process
GO:0070105Positive regulation of interleukin-6-mediated signaling pathwayIDAbiological_process
GO:0071222Cellular response to lipopolysaccharideIEPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.10990159570.95866377800.68727011171.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1559657278
GSE13712_SHEARUp0.0224654797
GSE13712_STATICDown-0.0839319249
GSE19018Up0.1641385167
GSE19899_A1Down-0.0910030691
GSE19899_A2Up0.1740177426
PubMed_21979375_A1Up0.1452417679
PubMed_21979375_A2Down-0.0631227021
GSE35957Up0.2582277022
GSE36640Up0.3100538466
GSE54402Up0.2443137692
GSE9593Up0.2826614137
GSE43922Up0.0248925421
GSE24585Up1.0208460173
GSE37065Down-0.0984396997
GSE28863_A1Down-0.1629756746
GSE28863_A2Up0.0814248117
GSE28863_A3Up0.3246199506
GSE28863_A4Up0.1278530684
GSE48662Up0.0093265716

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.