HCSGD entry for AMFR


1. General information

Official gene symbolAMFR
Entrez ID267
Gene full nameautocrine motility factor receptor, E3 ubiquitin protein ligase
Other gene symbolsGP78 RNF45
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000209Protein polyubiquitinationIDAbiological_process
GO:0004842Ubiquitin-protein ligase activityIDA IEA IMPmolecular_function
GO:0004872Receptor activityIPImolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIEAcellular_component
GO:0005737CytoplasmIEAcellular_component
GO:0006511Ubiquitin-dependent protein catabolic processIMPbiological_process
GO:0006928Cellular component movementTASbiological_process
GO:0007165Signal transductionTASbiological_process
GO:0007568AgingIEAbiological_process
GO:0007611Learning or memoryIEAbiological_process
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0016021Integral component of membraneNAScellular_component
GO:0030176Integral component of endoplasmic reticulum membraneIDAcellular_component
GO:0030425DendriteIEAcellular_component
GO:0030426Growth coneIEAcellular_component
GO:0030433ER-associated ubiquitin-dependent protein catabolic processIDA IMPbiological_process
GO:0030968Endoplasmic reticulum unfolded protein responseIMPbiological_process
GO:0043025Neuronal cell bodyIEAcellular_component
GO:0043234Protein complexIDAcellular_component
GO:0048471Perinuclear region of cytoplasmIDAcellular_component
GO:0051259Protein oligomerizationIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.10700541770.25902563350.67949085650.9762158935

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.3235174644
GSE13712_SHEARUp0.1082276906
GSE13712_STATICUp0.1732142344
GSE19018Up0.2521601907
GSE19899_A1Down-0.2770323524
GSE19899_A2Up0.2280680473
PubMed_21979375_A1Up0.3754505686
PubMed_21979375_A2Up0.5855667896
GSE35957Down-0.4705055821
GSE36640Up0.8086903850
GSE54402Down-0.2973984658
GSE9593Up0.5523874499
GSE43922Down-0.0413761560
GSE24585Down-0.1396853625
GSE37065Down-0.0176670002
GSE28863_A1Down-0.0400917673
GSE28863_A2Down-0.0189335696
GSE28863_A3Down-0.8016734802
GSE28863_A4Down-0.0027001359
GSE48662Up0.2656468462

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.