HCSGD entry for SLC17A5
1. General information
| Official gene symbol | SLC17A5 |
|---|---|
| Entrez ID | 26503 |
| Gene full name | solute carrier family 17 (anion/sugar transporter), member 5 |
| Other gene symbols | AST ISSD NSD SD SIALIN SIASD SLD |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005351 | Sugar:hydrogen symporter activity | TAS | molecular_function |
| GO:0005765 | Lysosomal membrane | IDA TAS | cellular_component |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0006811 | Ion transport | TAS | biological_process |
| GO:0006812 | Cation transport | TAS | biological_process |
| GO:0006820 | Anion transport | TAS | biological_process |
| GO:0006865 | Amino acid transport | IEA | biological_process |
| GO:0008643 | Carbohydrate transport | TAS | biological_process |
| GO:0015136 | Sialic acid transmembrane transporter activity | IDA | molecular_function |
| GO:0015739 | Sialic acid transport | IDA | biological_process |
| GO:0015992 | Proton transport | TAS | biological_process |
| GO:0016020 | Membrane | TAS | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0030054 | Cell junction | IEA | cellular_component |
| GO:0030672 | Synaptic vesicle membrane | IEA | cellular_component |
| GO:0034219 | Carbohydrate transmembrane transport | TAS | biological_process |
| GO:0034220 | Ion transmembrane transport | IDA | biological_process |
| GO:0055085 | Transmembrane transport | IEA TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0019853539 | 0.8363084989 | 0.1198543578 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.8197781810 |
| GSE13712_SHEAR | Down | -0.4085823403 |
| GSE13712_STATIC | Down | -0.0343980131 |
| GSE19018 | Up | 0.9560314186 |
| GSE19899_A1 | Up | 0.4356712901 |
| GSE19899_A2 | Up | 0.7621340516 |
| PubMed_21979375_A1 | Up | 0.4475932804 |
| PubMed_21979375_A2 | Up | 0.7072973313 |
| GSE35957 | Up | 0.4187872356 |
| GSE36640 | Up | 1.9637873898 |
| GSE54402 | Down | -0.1805326578 |
| GSE9593 | Up | 1.3987889551 |
| GSE43922 | Up | 0.3754680966 |
| GSE24585 | Up | 0.1644713095 |
| GSE37065 | Up | 0.6079879962 |
| GSE28863_A1 | Down | -0.4062333642 |
| GSE28863_A2 | Up | 0.7281852812 |
| GSE28863_A3 | Down | -1.2680837366 |
| GSE28863_A4 | Up | 0.0138138696 |
| GSE48662 | Up | 0.3117990311 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT002576 | Microarray | Functional MTI (Weak) | 15685193 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT002576 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-335-5p | MIMAT0000765 | MIRT018617 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-98-5p | MIMAT0000096 | MIRT027706 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029983 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-21-5p | MIMAT0000076 | MIRT030990 | Microarray | Functional MTI (Weak) | 18591254 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 699897 | Despite the wide variation in Pn5 activity, AST levels were maintained within relatively narrow limits |
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