HCSGD entry for PLEK2
1. General information
| Official gene symbol | PLEK2 |
|---|---|
| Entrez ID | 26499 |
| Gene full name | pleckstrin 2 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005856 | Cytoskeleton | IEA | cellular_component |
| GO:0030036 | Actin cytoskeleton organization | TAS | biological_process |
| GO:0031258 | Lamellipodium membrane | IEA | cellular_component |
| GO:0035556 | Intracellular signal transduction | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0000347783 | 0.3301074997 | 0.0166436364 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.8603954666 |
| GSE13712_SHEAR | Up | 0.9340030041 |
| GSE13712_STATIC | Up | 1.4712560105 |
| GSE19018 | Down | -0.0620678713 |
| GSE19899_A1 | Up | 3.0975638447 |
| GSE19899_A2 | Up | 5.0518779370 |
| PubMed_21979375_A1 | Up | 5.7072551728 |
| PubMed_21979375_A2 | Up | 6.1522784175 |
| GSE35957 | Down | -0.8215590529 |
| GSE36640 | Down | -1.7453454527 |
| GSE54402 | Up | 4.9692815951 |
| GSE9593 | Down | -0.1108398399 |
| GSE43922 | Up | 3.7642512224 |
| GSE24585 | Up | 1.0694478416 |
| GSE37065 | Down | -0.1673956617 |
| GSE28863_A1 | Down | -0.1433456925 |
| GSE28863_A2 | Down | -0.9538281628 |
| GSE28863_A3 | Down | -0.2278319035 |
| GSE28863_A4 | Up | 0.2826268552 |
| GSE48662 | Down | -0.7594895897 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-193b-3p | MIMAT0002819 | MIRT016423 | Microarray | Functional MTI (Weak) | 20304954 |
| hsa-miR-138-5p | MIMAT0000430 | MIRT021685 | qRT-PCR | Functional MTI (Weak) | 21770894 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
