HCSGD entry for LHX6

1. General information

Official gene symbolLHX6
Entrez ID26468
Gene full nameLIM homeobox 6
Other gene symbolsLHX6.1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003700Sequence-specific DNA binding transcription factor activityNASmolecular_function
GO:0005634NucleusIDA IEAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0021799Cerebral cortex radially oriented cell migrationIEA ISSbiological_process
GO:0021800Cerebral cortex tangential migrationIEA ISSbiological_process
GO:0021853Cerebral cortex GABAergic interneuron migrationIEA ISSbiological_process
GO:0021877Forebrain neuron fate commitmentIEAbiological_process
GO:0021884Forebrain neuron developmentIEAbiological_process
GO:0043565Sequence-specific DNA bindingIEAmolecular_function
GO:0048469Cell maturationIEA ISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.13027505790.87303455420.73331261761.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0739357445
GSE13712_SHEARDown-0.6730375184
GSE13712_STATICUp1.3762517288
GSE19018Up0.0858204346
GSE19899_A1Down-0.0170978639
GSE19899_A2Up0.0866399122
PubMed_21979375_A1Down-0.3271555400
PubMed_21979375_A2Down-0.0724258835
GSE35957Up0.2224664477
GSE36640Down-0.0107403609
GSE54402Up0.0508037198
GSE9593Up0.0905659190
GSE43922Up0.0665483550
GSE24585Up0.1787055789
GSE37065Down-0.0221065412
GSE28863_A1Up0.0299480485
GSE28863_A2Down-0.0097159645
GSE28863_A3Up0.5794078330
GSE28863_A4Up0.1410367207
GSE48662Up0.0477341391

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT016904MicroarrayFunctional MTI (Weak)18185580
hsa-miR-26b-5pMIMAT0000083MIRT028799MicroarrayFunctional MTI (Weak)19088304
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.