HCSGD entry for GBP1
1. General information
| Official gene symbol | GBP1 |
|---|---|
| Entrez ID | 2633 |
| Gene full name | guanylate binding protein 1, interferon-inducible |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000139 | Golgi membrane | IEA | cellular_component |
| GO:0003924 | GTPase activity | IEA | molecular_function |
| GO:0005525 | GTP binding | IEA | molecular_function |
| GO:0005576 | Extracellular region | IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0019221 | Cytokine-mediated signaling pathway | TAS | biological_process |
| GO:0042802 | Identical protein binding | IPI | molecular_function |
| GO:0051607 | Defense response to virus | IEA | biological_process |
| GO:0060333 | Interferon-gamma-mediated signaling pathway | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9877038486 | 0.0003962729 | 0.9999902473 | 0.0369868794 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -1.2939161581 |
| GSE13712_SHEAR | Up | 0.3283044240 |
| GSE13712_STATIC | Up | 0.4514310187 |
| GSE19018 | Down | -0.7591331709 |
| GSE19899_A1 | Down | -2.1266315846 |
| GSE19899_A2 | Down | -1.9914493372 |
| PubMed_21979375_A1 | Down | -3.6166652837 |
| PubMed_21979375_A2 | Down | -3.2443991645 |
| GSE35957 | Down | -0.4404534345 |
| GSE36640 | Up | 0.0681558006 |
| GSE54402 | Down | -1.3834529153 |
| GSE9593 | Down | -0.6150983337 |
| GSE43922 | - | - |
| GSE24585 | - | - |
| GSE37065 | - | - |
| GSE28863_A1 | Up | 0.2407917439 |
| GSE28863_A2 | Up | 0.2483224637 |
| GSE28863_A3 | Down | -0.2341142480 |
| GSE28863_A4 | Down | -0.1062912856 |
| GSE48662 | Down | -1.2773792140 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022397 | Microarray | Functional MTI (Weak) | 18668037 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
