HCSGD entry for ANKRD2


1. General information

Official gene symbolANKRD2
Entrez ID26287
Gene full nameankyrin repeat domain 2 (stretch responsive muscle)
Other gene symbolsARPP
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000791EuchromatinISScellular_component
GO:0005634NucleusIDAcellular_component
GO:0005829CytosolIDAcellular_component
GO:0006936Muscle contractionNASbiological_process
GO:0007517Muscle organ developmentNASbiological_process
GO:0008307Structural constituent of muscleNASmolecular_function
GO:0016605PML bodyIEAcellular_component
GO:0031432Titin bindingIEAmolecular_function
GO:0031674I bandISScellular_component
GO:0035914Skeletal muscle cell differentiationIEAbiological_process
GO:0043231Intracellular membrane-bounded organelleIDAcellular_component
GO:0043422Protein kinase B bindingIPImolecular_function
GO:0045662Negative regulation of myoblast differentiationIMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.89641524640.16210579390.99999024730.7777591323

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1255068274
GSE13712_SHEARDown-0.2145184404
GSE13712_STATICDown-0.2494068580
GSE19018Down-0.0039466209
GSE19899_A1Down-0.0673089923
GSE19899_A2Down-0.0301928526
PubMed_21979375_A1Up0.1224948921
PubMed_21979375_A2Up0.0109662067
GSE35957Down-0.0650876379
GSE36640Down-0.6604712119
GSE54402Up0.0227198968
GSE9593Down-0.1610460705
GSE43922Up0.0587964607
GSE24585Down-0.0230463526
GSE37065Down-0.1336195251
GSE28863_A1Down-0.1270583732
GSE28863_A2Down-0.3045385310
GSE28863_A3Up0.4031438445
GSE28863_A4Up0.0535299900
GSE48662Down-0.2125715075

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-27b-3pMIMAT0000419MIRT046215CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.