HCSGD entry for HIBCH
1. General information
| Official gene symbol | HIBCH |
|---|---|
| Entrez ID | 26275 |
| Gene full name | 3-hydroxyisobutyryl-CoA hydrolase |
| Other gene symbols | HIBYLCOAH |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003824 | Catalytic activity | IEA | molecular_function |
| GO:0003860 | 3-hydroxyisobutyryl-CoA hydrolase activity | IDA | molecular_function |
| GO:0005739 | Mitochondrion | IEA | cellular_component |
| GO:0005759 | Mitochondrial matrix | TAS | cellular_component |
| GO:0006574 | Valine catabolic process | IEA | biological_process |
| GO:0009083 | Branched-chain amino acid catabolic process | TAS | biological_process |
| GO:0034641 | Cellular nitrogen compound metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5963711561 | 0.1294501805 | 0.9999902473 | 0.6929546878 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2364430030 |
| GSE13712_SHEAR | Up | 0.0612801418 |
| GSE13712_STATIC | Up | 0.1741128133 |
| GSE19018 | Down | -0.1460668246 |
| GSE19899_A1 | Up | 0.2788288761 |
| GSE19899_A2 | Down | -0.3023662075 |
| PubMed_21979375_A1 | Down | -0.9298507623 |
| PubMed_21979375_A2 | Down | -0.5683121309 |
| GSE35957 | Up | 0.6409967123 |
| GSE36640 | Up | 0.5461738093 |
| GSE54402 | Down | -0.5447473315 |
| GSE9593 | Down | -0.2021586009 |
| GSE43922 | Down | -0.2588587306 |
| GSE24585 | Down | -0.0281461779 |
| GSE37065 | Up | 0.0563538238 |
| GSE28863_A1 | Up | 0.0366980477 |
| GSE28863_A2 | Down | -0.0293585523 |
| GSE28863_A3 | Down | -0.1241481744 |
| GSE28863_A4 | Down | -0.0982547593 |
| GSE48662 | Down | -0.3246386482 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Quercetin | DB04216 | EXPT02732 |
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
