HCSGD entry for FBXO3
1. General information
| Official gene symbol | FBXO3 |
|---|---|
| Entrez ID | 26273 |
| Gene full name | F-box protein 3 |
| Other gene symbols | FBA FBX3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004842 | Ubiquitin-protein ligase activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0006508 | Proteolysis | IEA | biological_process |
| GO:0016567 | Protein ubiquitination | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2862570647 | 0.6536119068 | 0.9857136709 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1098407091 |
| GSE13712_SHEAR | Down | -0.1578004147 |
| GSE13712_STATIC | Up | 0.0357519619 |
| GSE19018 | Up | 0.2903000849 |
| GSE19899_A1 | Up | 0.2561265206 |
| GSE19899_A2 | Up | 0.3070543235 |
| PubMed_21979375_A1 | Down | -0.1116727601 |
| PubMed_21979375_A2 | Up | 0.2986734314 |
| GSE35957 | Up | 0.3112060696 |
| GSE36640 | Up | 0.1836748181 |
| GSE54402 | Down | -0.0471192681 |
| GSE9593 | Up | 0.0390167052 |
| GSE43922 | Down | -0.0970909796 |
| GSE24585 | Up | 0.3015641413 |
| GSE37065 | Up | 0.1282259251 |
| GSE28863_A1 | Up | 0.0502054965 |
| GSE28863_A2 | Up | 0.2976359295 |
| GSE28863_A3 | Down | -0.8637672297 |
| GSE28863_A4 | Up | 0.0124428356 |
| GSE48662 | Down | -0.2691806756 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-142-3p | MIMAT0000434 | MIRT021627 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-30b-5p | MIMAT0000420 | MIRT023410 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026514 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029469 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-21-5p | MIMAT0000076 | MIRT030802 | Microarray | Functional MTI (Weak) | 18591254 |
| hsa-let-7d-5p | MIMAT0000065 | MIRT032115 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-20a-5p | MIMAT0000075 | MIRT050537 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT051071 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-15a-5p | MIMAT0000068 | MIRT051338 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
