HCSGD entry for FBXO25
1. General information
| Official gene symbol | FBXO25 |
|---|---|
| Entrez ID | 26260 |
| Gene full name | F-box protein 25 |
| Other gene symbols | FBX25 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000151 | Ubiquitin ligase complex | NAS | cellular_component |
| GO:0003779 | Actin binding | IEA | molecular_function |
| GO:0004842 | Ubiquitin-protein ligase activity | NAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA IEA ISS | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0016567 | Protein ubiquitination | ISS NAS | biological_process |
| GO:0019005 | SCF ubiquitin ligase complex | IEA ISS | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9660311690 | 0.0046969758 | 0.9999902473 | 0.1389091011 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0616539963 |
| GSE13712_SHEAR | Down | -3.3991263782 |
| GSE13712_STATIC | Down | -2.3656473200 |
| GSE19018 | Up | 0.5138486023 |
| GSE19899_A1 | Down | -0.4059714210 |
| GSE19899_A2 | Down | -0.6695754053 |
| PubMed_21979375_A1 | Down | -0.9416715674 |
| PubMed_21979375_A2 | Down | -0.7760159910 |
| GSE35957 | Up | 0.1504830834 |
| GSE36640 | Down | -0.0843211830 |
| GSE54402 | Down | -0.4581035540 |
| GSE9593 | Up | 0.8120238578 |
| GSE43922 | Down | -0.4561753183 |
| GSE24585 | Down | -0.1605092215 |
| GSE37065 | Down | -0.2859752335 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Down | -0.1171035247 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-215-5p | MIMAT0000272 | MIRT024524 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026896 | Microarray | Functional MTI (Weak) | 19074876 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
