HCSGD entry for INTS1
1. General information
| Official gene symbol | INTS1 |
|---|---|
| Entrez ID | 26173 |
| Gene full name | integrator complex subunit 1 |
| Other gene symbols | INT1 NET28 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001833 | Inner cell mass cell proliferation | IEA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016180 | SnRNA processing | IDA | biological_process |
| GO:0031965 | Nuclear membrane | IEA | cellular_component |
| GO:0032039 | Integrator complex | IDA | cellular_component |
| GO:0034474 | U2 snRNA 3'-end processing | IEA | biological_process |
| GO:0043066 | Negative regulation of apoptotic process | IEA | biological_process |
| GO:0043154 | Negative regulation of cysteine-type endopeptidase activity involved in apoptotic process | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3508355724 | 0.5381352456 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0209616346 |
| GSE13712_SHEAR | Up | 0.0337630377 |
| GSE13712_STATIC | Up | 0.0000660946 |
| GSE19018 | Up | 0.3222037426 |
| GSE19899_A1 | Down | -0.0335448126 |
| GSE19899_A2 | Down | -0.2406060767 |
| PubMed_21979375_A1 | Down | -0.6202454572 |
| PubMed_21979375_A2 | Up | 0.3160790221 |
| GSE35957 | Down | -0.2190976553 |
| GSE36640 | Down | -0.0368170468 |
| GSE54402 | Up | 0.2157072651 |
| GSE9593 | Down | -0.0580292635 |
| GSE43922 | Up | 0.0501244095 |
| GSE24585 | Down | -0.1378088483 |
| GSE37065 | Down | -0.1517842456 |
| GSE28863_A1 | Up | 0.3669474690 |
| GSE28863_A2 | Up | 0.5615317552 |
| GSE28863_A3 | Up | 0.1127865053 |
| GSE28863_A4 | Down | -0.1008550148 |
| GSE48662 | Down | -0.1490792421 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-877-5p | MIMAT0004949 | MIRT037241 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-769-3p | MIMAT0003887 | MIRT039110 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-769-5p | MIMAT0003886 | MIRT039214 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT039713 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT052201 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
