HCSGD entry for RGS22
1. General information
| Official gene symbol | RGS22 |
|---|---|
| Entrez ID | 26166 |
| Gene full name | regulator of G-protein signaling 22 |
| Other gene symbols | PRTD-NY2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005096 | GTPase activator activity | IBA | molecular_function |
| GO:0005737 | Cytoplasm | IBA | cellular_component |
| GO:0005886 | Plasma membrane | IBA | cellular_component |
| GO:0038032 | Termination of G-protein coupled receptor signaling pathway | IEA | biological_process |
| GO:0043085 | Positive regulation of catalytic activity | IBA | biological_process |
| GO:0043547 | Positive regulation of GTPase activity | IBA | biological_process |
| GO:0050790 | Regulation of catalytic activity | IBA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6150635462 | 0.8779941416 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0988104219 |
| GSE13712_SHEAR | Down | -0.0190490644 |
| GSE13712_STATIC | Down | -0.0837451192 |
| GSE19018 | Up | 0.1503235084 |
| GSE19899_A1 | Up | 0.0887843453 |
| GSE19899_A2 | Up | 0.0452919591 |
| PubMed_21979375_A1 | Up | 0.2947091244 |
| PubMed_21979375_A2 | Up | 0.1246682653 |
| GSE35957 | Up | 0.1380914259 |
| GSE36640 | Up | 0.3778478711 |
| GSE54402 | Down | -0.0511865179 |
| GSE9593 | Down | -0.0574770658 |
| GSE43922 | Up | 0.0230953736 |
| GSE24585 | Up | 0.1946878023 |
| GSE37065 | Down | -0.0295188043 |
| GSE28863_A1 | Down | -0.0184261693 |
| GSE28863_A2 | Down | -0.0266484989 |
| GSE28863_A3 | Up | 0.0516188547 |
| GSE28863_A4 | Down | -0.0354925304 |
| GSE48662 | Down | -0.1048570345 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018202 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
