HCSGD entry for TTLL3
1. General information
| Official gene symbol | TTLL3 |
|---|---|
| Entrez ID | 26140 |
| Gene full name | tubulin tyrosine ligase-like family, member 3 |
| Other gene symbols | HOTTL |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005874 | Microtubule | IEA | cellular_component |
| GO:0005929 | Cilium | ISS | cellular_component |
| GO:0005930 | Axoneme | ISS | cellular_component |
| GO:0006464 | Cellular protein modification process | IEA | biological_process |
| GO:0015630 | Microtubule cytoskeleton | ISS | cellular_component |
| GO:0018094 | Protein polyglycylation | IDA | biological_process |
| GO:0035082 | Axoneme assembly | ISS | biological_process |
| GO:0042384 | Cilium assembly | ISS | biological_process |
| GO:0070735 | Protein-glycine ligase activity | IDA | molecular_function |
| GO:0070736 | Protein-glycine ligase activity, initiating | ISS | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8990365944 | 0.6166407469 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1151087333 |
| GSE13712_SHEAR | Down | -0.0083303689 |
| GSE13712_STATIC | Down | -0.0149497354 |
| GSE19018 | Up | 0.0481285231 |
| GSE19899_A1 | Down | -0.0255519666 |
| GSE19899_A2 | Down | -0.0406850958 |
| PubMed_21979375_A1 | Down | -0.1684926527 |
| PubMed_21979375_A2 | Down | -0.0447637591 |
| GSE35957 | Up | 0.0234662688 |
| GSE36640 | Up | 0.1996987542 |
| GSE54402 | Down | -0.1315381993 |
| GSE9593 | Down | -0.0988871695 |
| GSE43922 | - | - |
| GSE24585 | - | - |
| GSE37065 | - | - |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Up | 0.2023725773 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022524 | Proteomics;Microarray | Non-Functional MTI (Weak) | 18668037 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
