HCSGD entry for PRPF31
1. General information
| Official gene symbol | PRPF31 |
|---|---|
| Entrez ID | 26121 |
| Gene full name | PRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae) |
| Other gene symbols | NY-BR-99 PRP31 RP11 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000244 | Spliceosomal tri-snRNP complex assembly | IDA IEA IMP | biological_process |
| GO:0000398 | MRNA splicing, via spliceosome | IC IDA | biological_process |
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005684 | U2-type spliceosomal complex | IC | cellular_component |
| GO:0005687 | U4 snRNP | IDA | cellular_component |
| GO:0005690 | U4atac snRNP | TAS | cellular_component |
| GO:0015030 | Cajal body | IDA | cellular_component |
| GO:0016607 | Nuclear speck | IDA | cellular_component |
| GO:0043021 | Ribonucleoprotein complex binding | IDA | molecular_function |
| GO:0046540 | U4/U6 x U5 tri-snRNP complex | IDA IEA | cellular_component |
| GO:0070990 | SnRNP binding | IPI | molecular_function |
| GO:0071339 | MLL1 complex | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9189388245 | 0.2001720603 | 0.9999902473 | 0.8652863853 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1457517424 |
| GSE13712_SHEAR | Down | -0.1854785810 |
| GSE13712_STATIC | Down | -0.0731231510 |
| GSE19018 | Up | 0.0660650863 |
| GSE19899_A1 | Down | -0.3110294338 |
| GSE19899_A2 | Up | 0.0233120887 |
| PubMed_21979375_A1 | Up | 0.0975783238 |
| PubMed_21979375_A2 | Down | -0.6179556549 |
| GSE35957 | Down | -0.1555402846 |
| GSE36640 | Down | -0.3782880262 |
| GSE54402 | Up | 0.1203471781 |
| GSE9593 | Down | -0.1642934757 |
| GSE43922 | Down | -0.0322651359 |
| GSE24585 | Down | -0.2512325583 |
| GSE37065 | Up | 0.0039257563 |
| GSE28863_A1 | Up | 0.0883000936 |
| GSE28863_A2 | Down | -0.0790494601 |
| GSE28863_A3 | Up | 0.0076334779 |
| GSE28863_A4 | Up | 0.1397768184 |
| GSE48662 | Down | -0.2811847583 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041299 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT041831 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
