HCSGD entry for WIPI2
1. General information
| Official gene symbol | WIPI2 |
|---|---|
| Entrez ID | 26100 |
| Gene full name | WD repeat domain, phosphoinositide interacting 2 |
| Other gene symbols | ATG18B Atg21 WIPI-2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000045 | Autophagic vacuole assembly | IMP | biological_process |
| GO:0000046 | Autophagic vacuole fusion | IMP | biological_process |
| GO:0000421 | Autophagic vacuole membrane | IBA | cellular_component |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005776 | Autophagic vacuole | IDA | cellular_component |
| GO:0005829 | Cytosol | IDA | cellular_component |
| GO:0032266 | Phosphatidylinositol-3-phosphate binding | IDA | molecular_function |
| GO:0034045 | Pre-autophagosomal structure membrane | IDA | cellular_component |
| GO:0043234 | Protein complex | IDA | cellular_component |
| GO:0080025 | Phosphatidylinositol-3,5-bisphosphate binding | IDA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0024954941 | 0.9940605676 | 0.1354307216 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.5093350532 |
| GSE13712_SHEAR | Up | 0.0442508750 |
| GSE13712_STATIC | Up | 0.0521829377 |
| GSE19018 | Up | 0.5752494745 |
| GSE19899_A1 | Up | 0.5362588051 |
| GSE19899_A2 | Up | 1.2659353991 |
| PubMed_21979375_A1 | Up | 1.4515457786 |
| PubMed_21979375_A2 | Up | 1.3887479035 |
| GSE35957 | Up | 0.3800383485 |
| GSE36640 | Up | 1.0733085099 |
| GSE54402 | Up | 0.5249005046 |
| GSE9593 | Up | 0.3173896349 |
| GSE43922 | Up | 0.4668299265 |
| GSE24585 | Up | 0.2391096555 |
| GSE37065 | Up | 0.0338179712 |
| GSE28863_A1 | Down | -0.0000609457 |
| GSE28863_A2 | Up | 0.3543065287 |
| GSE28863_A3 | Down | -0.4438736979 |
| GSE28863_A4 | Down | -0.2753740583 |
| GSE48662 | Up | 0.4434754929 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-505-5p | MIMAT0004776 | MIRT037966 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040290 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7a-5p | MIMAT0000062 | MIRT052545 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
