HCSGD entry for HACL1
1. General information
| Official gene symbol | HACL1 |
|---|---|
| Entrez ID | 26061 |
| Gene full name | 2-hydroxyacyl-CoA lyase 1 |
| Other gene symbols | 2-HPCL HPCL HPCL2 PHYH2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000287 | Magnesium ion binding | IEA | molecular_function |
| GO:0001561 | Fatty acid alpha-oxidation | IDA TAS | biological_process |
| GO:0003824 | Catalytic activity | IEA | molecular_function |
| GO:0005102 | Receptor binding | IPI | molecular_function |
| GO:0005777 | Peroxisome | IDA | cellular_component |
| GO:0005782 | Peroxisomal matrix | TAS | cellular_component |
| GO:0016829 | Lyase activity | IEA | molecular_function |
| GO:0016830 | Carbon-carbon lyase activity | IDA TAS | molecular_function |
| GO:0030976 | Thiamine pyrophosphate binding | IDA IEA | molecular_function |
| GO:0042802 | Identical protein binding | IPI | molecular_function |
| GO:0044255 | Cellular lipid metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0048037 | Cofactor binding | IDA | molecular_function |
| GO:0051259 | Protein oligomerization | IDA | biological_process |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0255768284 | 0.6290535998 | 0.3752551282 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0942477940 |
| GSE13712_SHEAR | Down | -0.2739802898 |
| GSE13712_STATIC | Down | -0.1112620490 |
| GSE19018 | Up | 0.3496592529 |
| GSE19899_A1 | Up | 0.5911666034 |
| GSE19899_A2 | Up | 0.7078103011 |
| PubMed_21979375_A1 | Up | 1.4589807668 |
| PubMed_21979375_A2 | Up | 1.3717323490 |
| GSE35957 | Down | -0.0139529934 |
| GSE36640 | Down | -0.0205261910 |
| GSE54402 | Up | 0.3141835360 |
| GSE9593 | Up | 0.2518798724 |
| GSE43922 | Up | 0.6343289135 |
| GSE24585 | Down | -0.1342800563 |
| GSE37065 | Up | 0.1264854501 |
| GSE28863_A1 | Down | -0.0039431324 |
| GSE28863_A2 | Up | 0.0782683244 |
| GSE28863_A3 | Down | -0.7332783804 |
| GSE28863_A4 | Down | -0.0844988805 |
| GSE48662 | Down | -0.4225019896 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-93-3p | MIMAT0004509 | MIRT038899 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-204-5p | MIMAT0000265 | MIRT047020 | CLASH | Functional MTI (Weak) | 23622248 |
Entries Per Page
Displaying Page of
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
