HCSGD entry for DNM3
1. General information
| Official gene symbol | DNM3 |
|---|---|
| Entrez ID | 26052 |
| Gene full name | dynamin 3 |
| Other gene symbols | Dyna III |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003924 | GTPase activity | IEA ISS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005525 | GTP binding | IEA | molecular_function |
| GO:0005739 | Mitochondrion | IEA | cellular_component |
| GO:0005874 | Microtubule | IEA | cellular_component |
| GO:0006184 | GTP catabolic process | ISS | biological_process |
| GO:0006897 | Endocytosis | ISS | biological_process |
| GO:0007416 | Synapse assembly | ISS | biological_process |
| GO:0008152 | Metabolic process | ISS | biological_process |
| GO:0014069 | Postsynaptic density | ISS | cellular_component |
| GO:0043197 | Dendritic spine | ISS | cellular_component |
| GO:0046847 | Filopodium assembly | ISS | biological_process |
| GO:0048471 | Perinuclear region of cytoplasm | ISS | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4198921204 | 0.8155877588 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0870410554 |
| GSE13712_SHEAR | Down | -0.8635827032 |
| GSE13712_STATIC | Down | -0.1039548651 |
| GSE19018 | Down | -0.1206203758 |
| GSE19899_A1 | Up | 0.0238072165 |
| GSE19899_A2 | Up | 0.1522663015 |
| PubMed_21979375_A1 | Up | 0.1832426585 |
| PubMed_21979375_A2 | Down | -0.0180500509 |
| GSE35957 | Up | 0.1899450126 |
| GSE36640 | Up | 0.1452688958 |
| GSE54402 | Up | 0.1947819861 |
| GSE9593 | Down | -0.1479664667 |
| GSE43922 | Up | 0.0170023240 |
| GSE24585 | Up | 0.4406920844 |
| GSE37065 | Up | 0.3156742022 |
| GSE28863_A1 | Up | 0.0657695785 |
| GSE28863_A2 | Up | 0.1991189804 |
| GSE28863_A3 | Up | 0.0776469746 |
| GSE28863_A4 | Down | -0.0180542320 |
| GSE48662 | Down | -0.1128918773 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022316 | Proteomics;Microarray | Functional MTI (Weak) | 18668037 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT032198 | Proteomics | Functional MTI (Weak) | 18668040 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
