HCSGD entry for PYDC1
1. General information
| Official gene symbol | PYDC1 |
|---|---|
| Entrez ID | 260434 |
| Gene full name | PYD (pyrin domain) containing 1 |
| Other gene symbols | ASC2 POP1 PYC1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005829 | Cytosol | IDA | cellular_component |
| GO:0006469 | Negative regulation of protein kinase activity | IDA | biological_process |
| GO:0008385 | IkappaB kinase complex | IDA | cellular_component |
| GO:0032088 | Negative regulation of NF-kappaB transcription factor activity | IDA | biological_process |
| GO:0033209 | Tumor necrosis factor-mediated signaling pathway | IDA | biological_process |
| GO:0045087 | Innate immune response | IDA | biological_process |
| GO:0050718 | Positive regulation of interleukin-1 beta secretion | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5598265377 | 0.6466594810 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0821066306 |
| GSE13712_SHEAR | Up | 0.0978761380 |
| GSE13712_STATIC | Down | -0.0402259133 |
| GSE19018 | Down | -0.0397557720 |
| GSE19899_A1 | Down | -0.0128664458 |
| GSE19899_A2 | Up | 0.0750463912 |
| PubMed_21979375_A1 | Down | -0.1400656758 |
| PubMed_21979375_A2 | Down | -0.0075539613 |
| GSE35957 | Down | -0.0850147986 |
| GSE36640 | Up | 0.1449816048 |
| GSE54402 | Up | 0.0683690843 |
| GSE9593 | Down | -0.0041723448 |
| GSE43922 | Up | 0.0125739401 |
| GSE24585 | Down | -0.0369439177 |
| GSE37065 | Down | -0.0015143180 |
| GSE28863_A1 | Up | 0.0295480460 |
| GSE28863_A2 | Up | 0.2995024092 |
| GSE28863_A3 | Up | 0.0263422425 |
| GSE28863_A4 | Up | 0.3389119318 |
| GSE48662 | Down | -0.1789994550 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
