HCSGD entry for PLEKHG3

1. General information

Official gene symbolPLEKHG3
Entrez ID26030
Gene full namepleckstrin homology domain containing, family G (with RhoGef domain) member 3
Other gene symbolsARHGEF43 KIAA0599
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005089Rho guanyl-nucleotide exchange factor activityIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.82434450440.68783211880.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0169722542
GSE13712_SHEARUp0.0721665169
GSE13712_STATICUp0.1082927423
GSE19018Up0.0999664536
GSE19899_A1Up0.0446906237
GSE19899_A2Down-0.0323517206
PubMed_21979375_A1Up0.1575903723
PubMed_21979375_A2Up0.0192788549
GSE35957Down-0.0749240060
GSE36640Down-0.2208100824
GSE54402Down-0.0052357003
GSE9593Up0.0339898632
GSE43922Up0.0253425796
GSE24585Down-0.2845760462
GSE37065Down-0.1366906553
GSE28863_A1Up0.0635563865
GSE28863_A2Up0.0031817624
GSE28863_A3Up0.0915382478
GSE28863_A4Up0.0813508626
GSE48662Down-0.1475097429

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018105MicroarrayFunctional MTI (Weak)18185580
hsa-miR-339-5pMIMAT0000764MIRT042767CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.