HCSGD entry for NALCN
1. General information
| Official gene symbol | NALCN |
|---|---|
| Entrez ID | 259232 |
| Gene full name | sodium leak channel, non-selective |
| Other gene symbols | CanIon VGCNL1 bA430M15.1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005216 | Ion channel activity | IEA | molecular_function |
| GO:0005244 | Voltage-gated ion channel activity | IEA | molecular_function |
| GO:0005272 | Sodium channel activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0034220 | Ion transmembrane transport | TAS | biological_process |
| GO:0035725 | Sodium ion transmembrane transport | TAS | biological_process |
| GO:0055085 | Transmembrane transport | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7795680939 | 0.0160169408 | 0.9999902473 | 0.2465391228 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1686370541 |
| GSE13712_SHEAR | Down | -0.3251982101 |
| GSE13712_STATIC | Up | 0.0772186382 |
| GSE19018 | Up | 0.0605693560 |
| GSE19899_A1 | Down | -0.0988934745 |
| GSE19899_A2 | Down | -0.8270380084 |
| PubMed_21979375_A1 | Down | -0.8540483935 |
| PubMed_21979375_A2 | Down | -0.9218196352 |
| GSE35957 | Up | 0.6900070394 |
| GSE36640 | Up | 1.1624113967 |
| GSE54402 | Down | -0.5547902650 |
| GSE9593 | Up | 0.2070200797 |
| GSE43922 | Down | -1.3974698125 |
| GSE24585 | Down | -0.7542595850 |
| GSE37065 | Down | -0.2150566394 |
| GSE28863_A1 | Down | -0.1116336155 |
| GSE28863_A2 | Down | -0.1046815615 |
| GSE28863_A3 | Down | -0.2957364660 |
| GSE28863_A4 | Up | 0.0106709762 |
| GSE48662 | Up | 0.4382143580 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-122-5p | MIMAT0000421 | MIRT023347 | Microarray | Functional MTI (Weak) | 17612493 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
