HCSGD entry for AMBP


1. General information

Official gene symbolAMBP
Entrez ID259
Gene full namealpha-1-microglobulin/bikunin precursor
Other gene symbolsA1M EDC1 HCP HI30 IATIL ITI ITIL ITILC UTI
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004867Serine-type endopeptidase inhibitor activityIEA TASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005576Extracellular regionIEA NAS TAScellular_component
GO:0005615Extracellular spaceIEAcellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0007155Cell adhesionNASbiological_process
GO:0007565Female pregnancyNASbiological_process
GO:0009986Cell surfaceIEAcellular_component
GO:0010951Negative regulation of endopeptidase activityTASbiological_process
GO:0016032Viral processIEAbiological_process
GO:0018298Protein-chromophore linkageIEAbiological_process
GO:0019855Calcium channel inhibitor activityNASmolecular_function
GO:0019862IgA bindingIDAmolecular_function
GO:0020037Heme bindingIDAmolecular_function
GO:0030163Protein catabolic processIEAbiological_process
GO:0036094Small molecule bindingIEAmolecular_function
GO:0042167Heme catabolic processNASbiological_process
GO:0042803Protein homodimerization activityIPImolecular_function
GO:0043231Intracellular membrane-bounded organelleIEAcellular_component
GO:0046329Negative regulation of JNK cascadeTASbiological_process
GO:0046904Calcium oxalate bindingNASmolecular_function
GO:0050777Negative regulation of immune responseNASbiological_process
GO:0052548Regulation of endopeptidase activityTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.84704695870.61521720300.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0760983500
GSE13712_SHEARDown-0.0241743085
GSE13712_STATICDown-0.1038784120
GSE19018Up0.0348754066
GSE19899_A1Down-0.0008233052
GSE19899_A2Up0.1425085639
PubMed_21979375_A1Down-0.1112399915
PubMed_21979375_A2Down-0.1138683118
GSE35957Up0.0983879953
GSE36640Down-0.0593028611
GSE54402Up0.0035141516
GSE9593Down-0.0898576033
GSE43922Up0.1377257285
GSE24585Down-0.1072743215
GSE37065Up0.0313172229
GSE28863_A1Down-0.0493937428
GSE28863_A2Down-0.2102831877
GSE28863_A3Up0.2521215168
GSE28863_A4Up0.0987179985
GSE48662Down-0.0514300930

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

Human Serum AlbuminDB00062 BTD00059 | BIOD00059
Serum albumin iodonatedDB00064 BTD00089 | BIOD00089

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.