HCSGD entry for PLEKHG4
1. General information
| Official gene symbol | PLEKHG4 |
|---|---|
| Entrez ID | 25894 |
| Gene full name | pleckstrin homology domain containing, family G (with RhoGef domain) member 4 |
| Other gene symbols | ARHGEF44 PRTPHN1 SCA4 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005089 | Rho guanyl-nucleotide exchange factor activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1742969720 | 0.3418122716 | 0.8196438549 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3912734714 |
| GSE13712_SHEAR | Up | 0.8543226384 |
| GSE13712_STATIC | Up | 0.8401685519 |
| GSE19018 | Down | -0.0689216904 |
| GSE19899_A1 | Down | -0.3180876304 |
| GSE19899_A2 | Down | -0.4514810092 |
| PubMed_21979375_A1 | Up | 0.0988688008 |
| PubMed_21979375_A2 | Down | -0.0829959452 |
| GSE35957 | Up | 0.5159478232 |
| GSE36640 | Up | 0.0065645929 |
| GSE54402 | Down | -0.7517372648 |
| GSE9593 | Up | 0.2809071944 |
| GSE43922 | Up | 0.0287012054 |
| GSE24585 | Up | 0.0244398594 |
| GSE37065 | Down | -0.0645377785 |
| GSE28863_A1 | Up | 0.1238436154 |
| GSE28863_A2 | Up | 0.0349887276 |
| GSE28863_A3 | Down | -0.1276631410 |
| GSE28863_A4 | Up | 0.0880527315 |
| GSE48662 | Down | -0.3769507893 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018367 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT022840 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-93-3p | MIMAT0004509 | MIRT038911 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-331-3p | MIMAT0000760 | MIRT043462 | CLASH | Functional MTI (Weak) | 23622248 |
Entries Per Page
Displaying Page of
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
