HCSGD entry for GALNS


1. General information

Official gene symbolGALNS
Entrez ID2588
Gene full namegalactosamine (N-acetyl)-6-sulfate sulfatase
Other gene symbolsGALNAC6S GAS GalN6S MPS4A
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003943N-acetylgalactosamine-4-sulfatase activityTASmolecular_function
GO:0005975Carbohydrate metabolic processTASbiological_process
GO:0008484Sulfuric ester hydrolase activityIDA IEAmolecular_function
GO:0030203Glycosaminoglycan metabolic processTASbiological_process
GO:0042339Keratan sulfate metabolic processTASbiological_process
GO:0042340Keratan sulfate catabolic processTASbiological_process
GO:0043202Lysosomal lumenTAScellular_component
GO:0043890N-acetylgalactosamine-6-sulfatase activityIEAmolecular_function
GO:0044281Small molecule metabolic processTASbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.32535735340.60734778690.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0953344689
GSE13712_SHEARDown-0.1567097577
GSE13712_STATICDown-0.2701284162
GSE19018Up0.0528642594
GSE19899_A1Down-0.1852620588
GSE19899_A2Up0.1812820993
PubMed_21979375_A1Down-0.2485527473
PubMed_21979375_A2Up0.3338209594
GSE35957Down-0.6119184695
GSE36640Up0.2101517576
GSE54402Down-0.0448755782
GSE9593Up0.3903044880
GSE43922Up0.0514968807
GSE24585Up0.1580976353
GSE37065Down-0.1499336989
GSE28863_A1Up0.1706329336
GSE28863_A2Up0.5234350310
GSE28863_A3Up0.0945275401
GSE28863_A4Down-0.0363260704
GSE48662Up0.5198905108

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.