HCSGD entry for USP49
1. General information
| Official gene symbol | USP49 |
|---|---|
| Entrez ID | 25862 |
| Gene full name | ubiquitin specific peptidase 49 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000398 | MRNA splicing, via spliceosome | IMP | biological_process |
| GO:0004197 | Cysteine-type endopeptidase activity | IMP | molecular_function |
| GO:0004221 | Ubiquitin thiolesterase activity | IDA IEA | molecular_function |
| GO:0004843 | Ubiquitin-specific protease activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0006511 | Ubiquitin-dependent protein catabolic process | IEA | biological_process |
| GO:0008234 | Cysteine-type peptidase activity | IEA | molecular_function |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0035616 | Histone H2B conserved C-terminal lysine deubiquitination | IDA | biological_process |
| GO:0042393 | Histone binding | IDA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7787596824 | 0.8029739144 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0049659958 |
| GSE13712_SHEAR | Up | 0.0209737055 |
| GSE13712_STATIC | Down | -0.0610929968 |
| GSE19018 | Up | 0.1759224501 |
| GSE19899_A1 | Up | 0.0066830183 |
| GSE19899_A2 | Down | -0.0882024562 |
| PubMed_21979375_A1 | Down | -0.0409536168 |
| PubMed_21979375_A2 | Down | -0.1081230834 |
| GSE35957 | Up | 0.0598631118 |
| GSE36640 | Up | 0.1711899351 |
| GSE54402 | Down | -0.0360919743 |
| GSE9593 | Up | 0.0648160526 |
| GSE43922 | Up | 0.0035613177 |
| GSE24585 | Up | 0.0778296075 |
| GSE37065 | Down | -0.0657363079 |
| GSE28863_A1 | Up | 0.3294281638 |
| GSE28863_A2 | Up | 0.2081718288 |
| GSE28863_A3 | Up | 0.0795778000 |
| GSE28863_A4 | Down | -0.1683936510 |
| GSE48662 | Down | -0.0667113742 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
