HCSGD entry for ARIH1
1. General information
| Official gene symbol | ARIH1 |
|---|---|
| Entrez ID | 25820 |
| Gene full name | ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila) |
| Other gene symbols | ARI HARI HHARI UBCH7BP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000151 | Ubiquitin ligase complex | TAS | cellular_component |
| GO:0004842 | Ubiquitin-protein ligase activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006511 | Ubiquitin-dependent protein catabolic process | TAS | biological_process |
| GO:0008270 | Zinc ion binding | IDA IEA | molecular_function |
| GO:0016567 | Protein ubiquitination | IDA | biological_process |
| GO:0019221 | Cytokine-mediated signaling pathway | TAS | biological_process |
| GO:0019787 | Small conjugating protein ligase activity | TAS | molecular_function |
| GO:0031625 | Ubiquitin protein ligase binding | IPI | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0326539911 | 0.9423930588 | 0.4168364341 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1893220545 |
| GSE13712_SHEAR | Down | -0.3404021357 |
| GSE13712_STATIC | Down | -0.0108395262 |
| GSE19018 | Up | 0.0715409624 |
| GSE19899_A1 | Up | 0.1130613152 |
| GSE19899_A2 | Up | 0.1693446479 |
| PubMed_21979375_A1 | Up | 0.1513863414 |
| PubMed_21979375_A2 | Up | 0.4301310455 |
| GSE35957 | Up | 0.2666155400 |
| GSE36640 | Up | 0.7627477033 |
| GSE54402 | Up | 0.1686151190 |
| GSE9593 | Up | 0.2569561091 |
| GSE43922 | Up | 0.0189287775 |
| GSE24585 | Up | 0.3538101558 |
| GSE37065 | Up | 0.1413080209 |
| GSE28863_A1 | Up | 0.6972934860 |
| GSE28863_A2 | Up | 0.6454818996 |
| GSE28863_A3 | Down | -0.6144460986 |
| GSE28863_A4 | Down | -0.2267535238 |
| GSE48662 | Up | 0.6623700722 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-425-5p | MIMAT0003393 | MIRT039312 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-17-5p | MIMAT0000070 | MIRT051051 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
