HCSGD entry for KLK5
1. General information
| Official gene symbol | KLK5 |
|---|---|
| Entrez ID | 25818 |
| Gene full name | kallikrein-related peptidase 5 |
| Other gene symbols | KLK-L2 KLKL2 SCTE |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004252 | Serine-type endopeptidase activity | IDA IEA NAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005615 | Extracellular space | TAS | cellular_component |
| GO:0006508 | Proteolysis | IEA | biological_process |
| GO:0008233 | Peptidase activity | TAS | molecular_function |
| GO:0008236 | Serine-type peptidase activity | TAS | molecular_function |
| GO:0008544 | Epidermis development | TAS | biological_process |
| GO:0045745 | Positive regulation of G-protein coupled receptor protein signaling pathway | IDA | biological_process |
| GO:0097209 | Epidermal lamellar body | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2776883857 | 0.8650876372 | 0.9749281046 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1217031246 |
| GSE13712_SHEAR | Down | -0.0824998744 |
| GSE13712_STATIC | Down | -0.0549298485 |
| GSE19018 | Up | 0.1486212957 |
| GSE19899_A1 | Up | 0.0599921800 |
| GSE19899_A2 | Up | 0.1275215484 |
| PubMed_21979375_A1 | Up | 0.2388524868 |
| PubMed_21979375_A2 | Down | -0.4967468045 |
| GSE35957 | Up | 0.2026400371 |
| GSE36640 | Up | 0.0519146019 |
| GSE54402 | Down | -0.0238721073 |
| GSE9593 | Down | -0.0602587921 |
| GSE43922 | Up | 0.0215460641 |
| GSE24585 | Up | 0.2399612697 |
| GSE37065 | Up | 0.2133297671 |
| GSE28863_A1 | Up | 0.0028295891 |
| GSE28863_A2 | Up | 0.1500900176 |
| GSE28863_A3 | Up | 0.5155796432 |
| GSE28863_A4 | Up | 0.1491771139 |
| GSE48662 | Down | -0.0522419656 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
