HCSGD entry for GALC
1. General information
| Official gene symbol | GALC |
|---|---|
| Entrez ID | 2581 |
| Gene full name | galactosylceramidase |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004336 | Galactosylceramidase activity | IEA ISS | molecular_function |
| GO:0005764 | Lysosome | TAS | cellular_component |
| GO:0005975 | Carbohydrate metabolic process | IEA | biological_process |
| GO:0006665 | Sphingolipid metabolic process | TAS | biological_process |
| GO:0006683 | Galactosylceramide catabolic process | IEA ISS | biological_process |
| GO:0006687 | Glycosphingolipid metabolic process | TAS | biological_process |
| GO:0043202 | Lysosomal lumen | TAS | cellular_component |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3574770639 | 0.0171774629 | 0.9999902473 | 0.2571082433 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.5727767739 |
| GSE13712_SHEAR | Down | -0.6028653273 |
| GSE13712_STATIC | Down | -0.5463927965 |
| GSE19018 | Down | -0.1117850137 |
| GSE19899_A1 | Down | -0.7372499660 |
| GSE19899_A2 | Down | -1.0637141779 |
| PubMed_21979375_A1 | Down | -1.4245072620 |
| PubMed_21979375_A2 | Down | -0.6053607862 |
| GSE35957 | Up | 0.1012197923 |
| GSE36640 | Up | 1.4834710480 |
| GSE54402 | Down | -0.9042382358 |
| GSE9593 | Up | 0.4210808790 |
| GSE43922 | Down | -0.6599839753 |
| GSE24585 | Up | 0.9800013061 |
| GSE37065 | Up | 0.3051500327 |
| GSE28863_A1 | Up | 0.2385966465 |
| GSE28863_A2 | Up | 0.4017770063 |
| GSE28863_A3 | Down | -0.2354788507 |
| GSE28863_A4 | Up | 0.0290444963 |
| GSE48662 | Up | 0.0563856238 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
