HCSGD entry for BAMBI
1. General information
| Official gene symbol | BAMBI |
|---|---|
| Entrez ID | 25805 |
| Gene full name | BMP and activin membrane-bound inhibitor homolog (Xenopus laevis) |
| Other gene symbols | NMA |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005109 | Frizzled binding | IPI | molecular_function |
| GO:0005114 | Type II transforming growth factor beta receptor binding | TAS | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005886 | Plasma membrane | IDA TAS | cellular_component |
| GO:0007179 | Transforming growth factor beta receptor signaling pathway | TAS | biological_process |
| GO:0008284 | Positive regulation of cell proliferation | IMP | biological_process |
| GO:0008360 | Regulation of cell shape | IMP | biological_process |
| GO:0010718 | Positive regulation of epithelial to mesenchymal transition | IMP | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016477 | Cell migration | IDA | biological_process |
| GO:0030512 | Negative regulation of transforming growth factor beta receptor signaling pathway | IDA IMP TAS | biological_process |
| GO:0032092 | Positive regulation of protein binding | IMP | biological_process |
| GO:0035413 | Positive regulation of catenin import into nucleus | IMP | biological_process |
| GO:0045893 | Positive regulation of transcription, DNA-templated | IDA | biological_process |
| GO:0090263 | Positive regulation of canonical Wnt signaling pathway | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0317397363 | 0.0964840280 | 0.4114814961 | 0.5919711189 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.5357184140 |
| GSE13712_SHEAR | Up | 0.6738364813 |
| GSE13712_STATIC | Down | -0.3073523254 |
| GSE19018 | Down | -0.6368724761 |
| GSE19899_A1 | Down | -0.4519384020 |
| GSE19899_A2 | Up | 0.8461036862 |
| PubMed_21979375_A1 | Up | 0.8184205852 |
| PubMed_21979375_A2 | Up | 0.9665288228 |
| GSE35957 | Up | 0.0784861390 |
| GSE36640 | Up | 2.6517668726 |
| GSE54402 | Down | -0.2888936886 |
| GSE9593 | Down | -0.2499655494 |
| GSE43922 | Up | 0.5994552030 |
| GSE24585 | Down | -0.3301418534 |
| GSE37065 | Up | 0.0056168685 |
| GSE28863_A1 | Down | -0.1605635622 |
| GSE28863_A2 | Down | -0.1185453988 |
| GSE28863_A3 | Up | 0.4012848833 |
| GSE28863_A4 | Up | 0.0321724918 |
| GSE48662 | Down | -0.0234221279 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-20b-5p | MIMAT0001413 | MIRT004121 | Luciferase reporter assay//qRT-PCR | Functional MTI | 21042576 |
| hsa-miR-374b-5p | MIMAT0004955 | MIRT016041 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-10a-5p | MIMAT0000253 | MIRT025596 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-1180-3p | MIMAT0005825 | MIRT035922 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-760 | MIMAT0004957 | MIRT036797 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT042246 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-106b-5p | MIMAT0000680 | MIRT044317 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-15b-5p | MIMAT0000417 | MIRT046515 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT051298 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
