HCSGD entry for QPCT
1. General information
| Official gene symbol | QPCT |
|---|---|
| Entrez ID | 25797 |
| Gene full name | glutaminyl-peptide cyclotransferase |
| Other gene symbols | GCT QC sQC |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005576 | Extracellular region | IEA | cellular_component |
| GO:0006464 | Cellular protein modification process | TAS | biological_process |
| GO:0006508 | Proteolysis | IEA | biological_process |
| GO:0008233 | Peptidase activity | IEA | molecular_function |
| GO:0008270 | Zinc ion binding | IDA | molecular_function |
| GO:0016603 | Glutaminyl-peptide cyclotransferase activity | IDA | molecular_function |
| GO:0017186 | Peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0000429733 | 0.8356430873 | 0.0188203125 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 1.4687117486 |
| GSE13712_SHEAR | Up | 0.3538010003 |
| GSE13712_STATIC | Up | 0.6347387785 |
| GSE19018 | Down | -0.9918455923 |
| GSE19899_A1 | Up | 4.4494393553 |
| GSE19899_A2 | Up | 4.2135112807 |
| PubMed_21979375_A1 | Up | 5.2195773154 |
| PubMed_21979375_A2 | Up | 4.3298246047 |
| GSE35957 | Up | 0.3963548443 |
| GSE36640 | Down | -1.1879304697 |
| GSE54402 | Up | 2.8229952891 |
| GSE9593 | Up | 0.7261514496 |
| GSE43922 | Up | 3.1966425548 |
| GSE24585 | Down | -0.0088566056 |
| GSE37065 | Up | 0.7687671971 |
| GSE28863_A1 | Down | -0.0145548972 |
| GSE28863_A2 | Up | 0.6845172496 |
| GSE28863_A3 | Down | -0.3059844778 |
| GSE28863_A4 | Down | -0.0539053493 |
| GSE48662 | Up | 0.1154607228 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| 1-benzylimidazole | DB04581 | - |
| N-ACETYLHISTAMINE | DB04622 | - |
| Glutamine t-butyl ester | DB04636 | - |
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 17893849 | The other type is the so-called spermatocytic seminomas (SS, type III GCT), composed of neoplastic primary spermatocytes |
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