HCSGD entry for FSCN2
1. General information
| Official gene symbol | FSCN2 |
|---|---|
| Entrez ID | 25794 |
| Gene full name | fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus) |
| Other gene symbols | RFSN RP30 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003779 | Actin binding | ISS | molecular_function |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0007601 | Visual perception | TAS | biological_process |
| GO:0009653 | Anatomical structure morphogenesis | TAS | biological_process |
| GO:0015629 | Actin cytoskeleton | ISS | cellular_component |
| GO:0030036 | Actin cytoskeleton organization | ISS | biological_process |
| GO:0030674 | Protein binding, bridging | IEA | molecular_function |
| GO:0032420 | Stereocilium | IEA | cellular_component |
| GO:0042462 | Eye photoreceptor cell development | IEA | biological_process |
| GO:0051015 | Actin filament binding | ISS | molecular_function |
| GO:0051017 | Actin filament bundle assembly | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1548315983 | 0.8953712549 | 0.7822116123 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0337933644 |
| GSE13712_SHEAR | Up | 0.0659506905 |
| GSE13712_STATIC | Down | -0.0148821496 |
| GSE19018 | Up | 0.0376563537 |
| GSE19899_A1 | Up | 0.1186264604 |
| GSE19899_A2 | Up | 0.1550355599 |
| PubMed_21979375_A1 | Up | 0.1859487100 |
| PubMed_21979375_A2 | Down | -0.2102221360 |
| GSE35957 | Down | -0.0593938516 |
| GSE36640 | Up | 0.0442090373 |
| GSE54402 | Up | 0.0507315535 |
| GSE9593 | Up | 0.0700087252 |
| GSE43922 | Up | 0.0578775160 |
| GSE24585 | Up | 0.3195268107 |
| GSE37065 | Down | -0.1376771994 |
| GSE28863_A1 | Down | -0.2617529891 |
| GSE28863_A2 | Down | -0.1076566519 |
| GSE28863_A3 | Up | 0.4788503720 |
| GSE28863_A4 | Up | 0.1034732815 |
| GSE48662 | Up | 1.5680229320 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT019017 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT051107 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
