HCSGD entry for RAD54B
1. General information
| Official gene symbol | RAD54B |
|---|---|
| Entrez ID | 25788 |
| Gene full name | RAD54 homolog B (S. cerevisiae) |
| Other gene symbols | RDH54 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000724 | Double-strand break repair via homologous recombination | IDA | biological_process |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003678 | DNA helicase activity | TAS | molecular_function |
| GO:0003724 | RNA helicase activity | TAS | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0006200 | ATP catabolic process | IDA | biological_process |
| GO:0006312 | Mitotic recombination | TAS | biological_process |
| GO:0007131 | Reciprocal meiotic recombination | TAS | biological_process |
| GO:0015616 | DNA translocase activity | IDA | molecular_function |
| GO:0032508 | DNA duplex unwinding | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9917243038 | 0.0033158125 | 0.9999902473 | 0.1163384820 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0795504781 |
| GSE13712_SHEAR | Down | -0.2069687858 |
| GSE13712_STATIC | Down | -0.1287577098 |
| GSE19018 | Down | -0.2346823361 |
| GSE19899_A1 | Down | -0.2840633715 |
| GSE19899_A2 | Down | -1.8363201140 |
| PubMed_21979375_A1 | Down | -0.6098200979 |
| PubMed_21979375_A2 | Down | -2.5200124561 |
| GSE35957 | Down | -1.7588466209 |
| GSE36640 | Down | -2.1102187417 |
| GSE54402 | Down | -0.1781346422 |
| GSE9593 | Down | -0.8231456064 |
| GSE43922 | - | - |
| GSE24585 | - | - |
| GSE37065 | - | - |
| GSE28863_A1 | Up | 0.0351669439 |
| GSE28863_A2 | Up | 0.2250727490 |
| GSE28863_A3 | Down | -0.3485889044 |
| GSE28863_A4 | Up | 0.1948875101 |
| GSE48662 | Down | -0.5909051718 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-215-5p | MIMAT0000272 | MIRT024274 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026800 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-346 | MIMAT0000773 | MIRT042701 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
