HCSGD entry for GABRR2
1. General information
| Official gene symbol | GABRR2 |
|---|---|
| Entrez ID | 2570 |
| Gene full name | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004890 | GABA-A receptor activity | IEA | molecular_function |
| GO:0005230 | Extracellular ligand-gated ion channel activity | IEA | molecular_function |
| GO:0005254 | Chloride channel activity | IEA | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0006810 | Transport | TAS | biological_process |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0007214 | Gamma-aminobutyric acid signaling pathway | IEA | biological_process |
| GO:0007268 | Synaptic transmission | TAS | biological_process |
| GO:0007601 | Visual perception | IEA | biological_process |
| GO:0019904 | Protein domain specific binding | IEA | molecular_function |
| GO:0030054 | Cell junction | IEA | cellular_component |
| GO:0034220 | Ion transmembrane transport | TAS | biological_process |
| GO:0034707 | Chloride channel complex | IEA | cellular_component |
| GO:0045211 | Postsynaptic membrane | IEA | cellular_component |
| GO:0055085 | Transmembrane transport | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5042371946 | 0.8839764523 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0702646849 |
| GSE13712_SHEAR | Up | 0.1205414824 |
| GSE13712_STATIC | Up | 0.0806868295 |
| GSE19018 | Up | 0.1164865081 |
| GSE19899_A1 | Down | -0.0115850749 |
| GSE19899_A2 | Up | 0.0685365302 |
| PubMed_21979375_A1 | Up | 0.2971897825 |
| PubMed_21979375_A2 | Down | -0.2901609196 |
| GSE35957 | Up | 0.0058975064 |
| GSE36640 | Up | 0.1741125133 |
| GSE54402 | Up | 0.1220446286 |
| GSE9593 | Up | 0.0184289396 |
| GSE43922 | Up | 0.0187455711 |
| GSE24585 | Up | 0.0196523044 |
| GSE37065 | Down | -0.0794233355 |
| GSE28863_A1 | Up | 0.0556087541 |
| GSE28863_A2 | Up | 0.1981836899 |
| GSE28863_A3 | Up | 0.2334722251 |
| GSE28863_A4 | Up | 0.0660382003 |
| GSE48662 | Down | -0.1246396438 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Temazepam | DB00231 | APRD00676 |
| Adinazolam | DB00546 | APRD00724 |
| Midazolam | DB00683 | APRD00680 |
| Flurazepam | DB00690 | APRD00983 |
| Halazepam | DB00801 | APRD01009 |
| Diazepam | DB00829 | APRD00642 | DB07699 |
| Oxazepam | DB00842 | APRD01152 |
| Triazolam | DB00897 | APRD00313 |
| Estazolam | DB01215 | APRD00955 |
| Bromazepam | DB01558 | - |
| Clotiazepam | DB01559 | - |
| Fludiazepam | DB01567 | - |
| Prazepam | DB01588 | - |
| Quazepam | DB01589 | - |
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
