HCSGD entry for ALX3


1. General information

Official gene symbolALX3
Entrez ID257
Gene full nameALX homeobox 3
Other gene symbolsFND1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003700Sequence-specific DNA binding transcription factor activityIEAmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0007389Pattern specification processIEAbiological_process
GO:0035115Embryonic forelimb morphogenesisIEAbiological_process
GO:0035116Embryonic hindlimb morphogenesisIEAbiological_process
GO:0042981Regulation of apoptotic processIEAbiological_process
GO:0043565Sequence-specific DNA bindingIEAmolecular_function
GO:0048704Embryonic skeletal system morphogenesisIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.60925696590.72283860040.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1337972159
GSE13712_SHEARDown-0.1385864365
GSE13712_STATICDown-0.0174839961
GSE19018Up0.1474741413
GSE19899_A1Down-0.0012798954
GSE19899_A2Up0.0737266778
PubMed_21979375_A1Up0.3260058190
PubMed_21979375_A2Down-0.1250179333
GSE35957Up0.1486639176
GSE36640Down-0.1231473331
GSE54402Up0.0104491896
GSE9593Down-0.0324701043
GSE43922Up0.2095650664
GSE24585Up0.0139257499
GSE37065Down-0.1478186605
GSE28863_A1Down-0.0293531334
GSE28863_A2Up0.0313790991
GSE28863_A3Up0.3241902005
GSE28863_A4Up0.1037155755
GSE48662Down-0.0603404258

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.