HCSGD entry for SERINC5
1. General information
| Official gene symbol | SERINC5 |
|---|---|
| Entrez ID | 256987 |
| Gene full name | serine incorporator 5 |
| Other gene symbols | C5orf12 TPO1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005789 | Endoplasmic reticulum membrane | IEA | cellular_component |
| GO:0005794 | Golgi apparatus | IEA | cellular_component |
| GO:0006658 | Phosphatidylserine metabolic process | ISS | biological_process |
| GO:0008654 | Phospholipid biosynthetic process | IEA | biological_process |
| GO:0016020 | Membrane | IEA | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0042552 | Myelination | IEA | biological_process |
| GO:0043209 | Myelin sheath | IEA | cellular_component |
| GO:0051347 | Positive regulation of transferase activity | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0029007561 | 0.9647500665 | 0.1443304348 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 1.2715824944 |
| GSE13712_SHEAR | Down | -0.3001918764 |
| GSE13712_STATIC | Up | 0.0596929901 |
| GSE19018 | Up | 0.4827913374 |
| GSE19899_A1 | Up | 0.6223671163 |
| GSE19899_A2 | Up | 0.6909640752 |
| PubMed_21979375_A1 | Up | 0.9868829555 |
| PubMed_21979375_A2 | Up | 0.4851640987 |
| GSE35957 | Down | -0.2612136413 |
| GSE36640 | Up | 0.8070943921 |
| GSE54402 | Up | 0.4858687888 |
| GSE9593 | Up | 0.9516140944 |
| GSE43922 | Up | 0.7580566817 |
| GSE24585 | Up | 0.4062110330 |
| GSE37065 | Down | -0.1870813990 |
| GSE28863_A1 | Down | -0.1670224976 |
| GSE28863_A2 | Up | 0.2072620513 |
| GSE28863_A3 | Down | -0.2089906834 |
| GSE28863_A4 | Down | -0.0270310079 |
| GSE48662 | Up | 0.5255125833 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-145-5p | MIMAT0000437 | MIRT021507 | Reporter assay;Microarray | Functional MTI | 21351259 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT051076 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
