HCSGD entry for GABRB1

1. General information

Official gene symbolGABRB1
Entrez ID2560
Gene full namegamma-aminobutyric acid (GABA) A receptor, beta 1
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004890GABA-A receptor activityIEAmolecular_function
GO:0005230Extracellular ligand-gated ion channel activityIEAmolecular_function
GO:0005254Chloride channel activityIEAmolecular_function
GO:0005886Plasma membraneIEA TAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0006810TransportTASbiological_process
GO:0006811Ion transportIEAbiological_process
GO:0007165Signal transductionTASbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0030054Cell junctionIEAcellular_component
GO:0034220Ion transmembrane transportTASbiological_process
GO:0034707Chloride channel complexIEAcellular_component
GO:0045202SynapseIEAcellular_component
GO:0045211Postsynaptic membraneIEAcellular_component
GO:0055085Transmembrane transportTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.54974375970.05884883930.99999024730.4568681108

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2044634008
GSE13712_SHEARDown-0.0492799305
GSE13712_STATICUp0.0262103792
GSE19018Up0.2120246485
GSE19899_A1Down-0.3767996634
GSE19899_A2Down-1.2487364679
PubMed_21979375_A1Down-0.3917084816
PubMed_21979375_A2Down-0.8800031893
GSE35957Down-0.0817343692
GSE36640Down-4.7294452345
GSE54402Up1.4756657161
GSE9593Up0.0013371613
GSE43922Down-0.4460588978
GSE24585Up0.1426419946
GSE37065Up0.0953796532
GSE28863_A1Up0.0274991762
GSE28863_A2Down-0.1270247279
GSE28863_A3Up0.1669990423
GSE28863_A4Up0.0396779892
GSE48662Up0.1161681824

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.