HCSGD entry for GABRA3

1. General information

Official gene symbolGABRA3
Entrez ID2556
Gene full namegamma-aminobutyric acid (GABA) A receptor, alpha 3
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004890GABA-A receptor activityIEAmolecular_function
GO:0005230Extracellular ligand-gated ion channel activityIEAmolecular_function
GO:0005254Chloride channel activityIEAmolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0006810TransportTASbiological_process
GO:0007214Gamma-aminobutyric acid signaling pathwayIEAbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0008503Benzodiazepine receptor activityTASmolecular_function
GO:0016021Integral component of membraneIEAcellular_component
GO:0030054Cell junctionIEAcellular_component
GO:0034220Ion transmembrane transportTASbiological_process
GO:0034707Chloride channel complexIEAcellular_component
GO:0045211Postsynaptic membraneIEAcellular_component
GO:0055085Transmembrane transportTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.76542142020.80718937350.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0400004354
GSE13712_SHEARDown-0.1369480286
GSE13712_STATICDown-0.0688725645
GSE19018Up0.0109010300
GSE19899_A1Up0.1018935250
GSE19899_A2Down-0.0218710500
PubMed_21979375_A1Up0.0626002876
PubMed_21979375_A2Up0.0828739199
GSE35957Up0.2669280731
GSE36640Down-0.0240026871
GSE54402Up0.1383313025
GSE9593Up0.0444081983
GSE43922Up0.0241409742
GSE24585Down-0.1005077351
GSE37065Up0.0161490916
GSE28863_A1Down-0.0217845674
GSE28863_A2Down-0.2607031106
GSE28863_A3Up0.1019379170
GSE28863_A4Up0.0496885293
GSE48662Down-0.0014250852

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-26b-5pMIMAT0000083MIRT029587MicroarrayFunctional MTI (Weak)19088304
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.